1.14.16.5: alkylglycerol monooxygenase

This is an abbreviated version!
For detailed information about alkylglycerol monooxygenase, go to the full flat file.

Reaction

Synonyms

AGMO, alkylglycerol mono-oxygenase, alkylglycerol monooxygenase, EC 1.14.99.17, glyceryl ether hydroxylase, glyceryl ether monooxygenase, glyceryl ether oxidase, glyceryl ether oxygenase, glyceryl ether-cleaving enzyme, glyceryl etherase, glyceryl-ether cleaving enzyme, O-alkylglycerol monooxygenase, oxygenase, glyceryl ether mono-, PRUB680

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.16.5 alkylglycerol monooxygenase

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Results	in table
6	Activating Compound
39	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
30	Cofactor
5	Disease/ Diagnostics
1	Expression
2	General Information
3	IC50 Value
61	Inhibitors
15	Ki Value [mM]
48	KM Value [mM]
24	Localization
5	Metals/Ions
8	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
41	Organism
5	pH Optimum
1	pH Range
24	Protein Variants
5	Purification (Commentary)
3	Reaction
4	Reaction Type
41	Reference
47	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
130	Substrates and Products (Substrate)
6	Subunits
24	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Disease

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Disease on EC 1.14.16.5 - alkylglycerol monooxygenase

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DISEASE

TITLE OF PUBLICATION

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Cataract

Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymes.

20643956

Leishmaniasis, Visceral

Exome Sequencing Identifies Two Variants of the Alkylglycerol Monooxygenase Gene as a Cause of Relapses in Visceral Leishmaniasis in Children, in Sudan.

28586473

Microcephaly

The alkylglycerol monooxygenase (AGMO) gene previously involved in autism also causes a novel syndromic form of primary microcephaly in a consanguineous Saudi family.

27000257

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