Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.16.2: tyrosine 3-monooxygenase

This is an abbreviated version!
For detailed information about tyrosine 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.16.2

Reaction

L-tyrosine
+
a 5,6,7,8-tetrahydropteridine
 +
O2
=
L-Dopa
 +
a 4a-hydroxy-5,6,7,8-tetrahydropteridine

Synonyms

CAT-2, DTH1, DTH2, hTH2, L-tyrosine hydroxylase, monophenol monooxygenase, oxygenase, tyrosine 3-mono-, TH, TH1, TH2, TyrH, tyrosinase, tyrosine 3-hydroxylase, tyrosine 3-monooxygenase, tyrosine hydroxylase, tyrosine hydroxylase type 1, tyrosine-3-mono-oxygenase, tyrosine-3-monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.16.2 tyrosine 3-monooxygenase

IC50 Value

IC50 Value on EC 1.14.16.2 - tyrosine 3-monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0022 - 0.0326
3,4-dihydroxy-L-phenylalanine
0.05
3-iodo-L-tyrosine
Homo sapiens
-
pH and temperature not specified in the publication
0.0002 - 0.0136
dopamine
0.0003
N-methyl-norsalsolinol
Homo sapiens
-
-
0.004
N-methyl-salsolinol
Homo sapiens
-
-
0.01
norsalsolinol
Homo sapiens
-
-