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1.14.15.11: pentalenic acid synthase

This is an abbreviated version!
For detailed information about pentalenic acid synthase, go to the full flat file.

Word Map on EC 1.14.15.11

Reaction

1-deoxypentalenate
+
reduced ferredoxin
 +
O2
=
pentalenate
 +
oxidized ferredoxin
 +
H2O

Synonyms

CYP105D7, CYP28, pentalenic acid synthase, sav7469, SAV_7469

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.11 pentalenic acid synthase

Crystallization

Crystallization on EC 1.14.15.11 - pentalenic acid synthase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
in complex with diclofenac, at 2.2 A resolution. The distal pocket of CYP105D7 contains two diclofenac molecules. The C3' and C4' atoms of the dichlorophenyl ring of one diclofenac molecule are positioned near the heme iron
molecular docking of compactin, compactin is directly hydrogen bonded with residues Thr79, Arg81, Leu178, Thr391, and Ile392 and its C6 position is proximate to the heme group. Molecular docking of diclofenac