1.14.14.56: 1,8-cineole 2-exo-monooxygenase

This is an abbreviated version!
For detailed information about 1,8-cineole 2-exo-monooxygenase, go to the full flat file.

Reaction

Synonyms

CYP3A4, CYP3A5, EC 1.14.13.157

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.56 1,8-cineole 2-exo-monooxygenase

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Results	in table
4	Activating Compound
2	AA Sequence
4	Cloned(Commentary)
1	General Information
3	Inhibitors
2	kcat/KM [mM/s]
9	KM Value [mM]
2	Localization
4	Organism
1	Pathway
57	PDB ID
1	Reaction
4	Reference
2	Source Tissue
7	Substrates and Products (Substrate)
6	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.14.14.56 - 1,8-cineole 2-exo-monooxygenase

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1,8-cineole,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (2-exo-hydroxylating)

A cytochrome P-450 (heme-thiolate) protein. The mammalian enzyme, expressed in liver microsomes, performs a variety of oxidation reactions of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. cf. EC 1.14.14.55, quinine 3-monooxygenase, EC 1.14.14.57, taurochenodeoxycholate 6-hydroxylase and EC 1.14.14.73, albendazole monooxygenase (sulfoxide-forming).