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1.14.14.50: tabersonine 3-oxygenase

This is an abbreviated version!
For detailed information about tabersonine 3-oxygenase, go to the full flat file.

Reaction

16-methoxytabersonine
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP71D1V2, T3O

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.50 tabersonine 3-oxygenase

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Resultsin table
2AA Sequence
1Organism
3Pathway
2Reaction
1Reference
2Source Tissue
2Substrates and Products (Substrate)
4Synonyms
1Systematic Name

Reference

Reference on EC 1.14.14.50 - tabersonine 3-oxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Qu, Y.; Easson, M.L.; Froese, J.; Simionescu, R.; Hudlicky, T.; De Luca, V.
Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast
Proc. Natl. Acad. Sci. USA
112
6224-6229
2015
Catharanthus roseus (I1TEM1), Catharanthus roseus
Manually annotated by BRENDA team