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1.14.14.43: (methylsulfanyl)alkanaldoxime N-monooxygenase

This is an abbreviated version!
For detailed information about (methylsulfanyl)alkanaldoxime N-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.43

Reaction

a 1-(methylsulfanyl)-4-aci-nitroalkane
+
glutathione
=
an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione
+
H2O

Synonyms

(methylthio)alkanaldoxime N-monooxygenase, CYP83A1, CYP83A1.1, cytochrome P450 CYP83A1, cytochrome P450 monooxygenase 83A1-2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.43 (methylsulfanyl)alkanaldoxime N-monooxygenase

Substrates Products

Substrates Products on EC 1.14.14.43 - (methylsulfanyl)alkanaldoxime N-monooxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(E)-4-hydroxyphenylacetaldoxime + O2 + [reduced NADPH-hemoprotein reductase]
1-aci-nitro-2-(4-hydroxyphenyl)-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
(E)-phenylacetaldoxime + O2 + [reduced NADPH-hemoprotein reductase]
1-aci-nitro-2-phenylethane + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
1-aci-nitro-2-(4-hydroxyphenyl)-ethane + 2-mercaptoethanol
(Z)-2-hydroxyethyl N-hydroxy-2-(4-hydroxyphenyl)ethanimidothioate + H2O
show the reaction diagram
-
-
-
?
indole-3-acetaldoxime + O2 + glutathione + [reduced NADPH-hemoprotein reductase]
1-aci-nitro-2-indolyl-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
additional information
?
-
isoform CYP83A1 catalyzes the initial conversion of aldoximes to thiohydroximates in the synthesis of glucosinolates not derived from tryptophan
-
-
?