1.14.14.40: phenylalanine N-monooxygenase

This is an abbreviated version!
For detailed information about phenylalanine N-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.40

1.14.14.40

glucosinolates

aldoxime

phenylacetaldoxime

benzyl

brassicales

indole-3-acetaldoxime

nitriles

phenylacetic

cyanogenic

prunus

benzylglucosinolate

iaa

indole-3-acetic

synthesis

Reaction

+ 2 [reduced NADPH-hemoprotein reductase] + 2 O2 =

+ 2 [oxidized NADPH-hemoprotein reductase] +

+ 3 H2O

Synonyms

CYP79A1, CYP79A2, CYP79D16, cytochrome P450 79D16, EC 1.14.13.124

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.40 phenylalanine N-monooxygenase

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Results	in table
4	Activating Compound
4	AA Sequence
1	Application
3	Cloned(Commentary)
3	Cofactor
2	General Information
1	KM Value [mM]
1	Localization
1	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
4	Organism
4	Pathway
1	pH Optimum
3	pH Range
4	Reaction
4	Reference
1	Source Tissue
11	Substrates and Products (Substrate)
1	Subunits
6	Synonyms
1	Systematic Name

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Reference on EC 1.14.14.40 - phenylalanine N-monooxygenase

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715445

Wittstock, U.; Halkier, B.

Cytochrome P450 CYP79A2 from Arabidopsis thaliana L. catalyzes the conversion of L-phenylalanine to phenylacetaldoxime in the biosynthesis of benzylglucosinolate

J. Biol. Chem.

275

14659-14666

2000

Arabidopsis thaliana (Q9FLC8), Arabidopsis thaliana

10799553

729046

Miki, Y.; Asano, Y.

Construction of the biosynthetic pathway for the cyanide-free production of phenylacetonitrile in Escherichia coli utilizing plant cytochrome P450 79A2 and bacterial aldoxime dehydratase

Appl. Environ. Microbiol.

6828-6836

2014

Arabidopsis thaliana (Q9FLC8), Arabidopsis thaliana

25172862

739318

Clausen, M.; Kannangara, R.M.; Olsen, C.E.; Blomstedt, C.K.; Gleadow, R.M.; Jorgensen, K.; Bak, S.; Motawie, M.S.; Moller, B.L.

The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways

Plant J.

558-573

2015

Sorghum bicolor

26361733

741183

Yamaguchi, T.; Yamamoto, K.; Asano, Y.

Identification and characterization of CYP79D16 and CYP71AN24 catalyzing the first and second steps in L-phenylalanine-derived cyanogenic glycoside biosynthesis in the Japanese apricot, Prunus mume Sieb. et Zucc

Plant Mol. Biol.

215-223

2014

Prunus mume (A0A068Q7V0), Prunus mume

25015725