Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.14.37: 4-hydroxyphenylacetaldehyde oxime monooxygenase

This is an abbreviated version!
For detailed information about 4-hydroxyphenylacetaldehyde oxime monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.37

Reaction

(E)-4-hydroxyphenylacetaldehyde oxime
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(S)-4-hydroxymandelonitrile
+
[oxidized NADPH-hemoprotein reductase]
+ 2 H2O

Synonyms

4-hydroxybenzeneacetaldehyde oxime monooxygenase, 4-hydroxyphenylacetaldehyde oxime monooxygenase, CYP71E, CYP71E1, cytochrome P450II-dependent monooxygenase, EC 1.14.13.42, EC 1.14.13.68, NADPH-cytochrome P450 reductase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.37 4-hydroxyphenylacetaldehyde oxime monooxygenase

Substrates Products

Substrates Products on EC 1.14.14.37 - 4-hydroxyphenylacetaldehyde oxime monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(E)-4-Hydroxyphenylacetaldehyde oxime
(Z)-4-Hydroxyphenylacetaldehyde oxime
show the reaction diagram
-
-
-
?
(E)-4-hydroxyphenylacetaldehyde oxime + [reduced NADPH-hemoprotein reductase] + O2
(S)-4-hydroxymandelonitrile + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
(E)-phenylacetaldehyde oxime + [reduced NADPH-hemoprotein reductase] + O2
(S)-mandelonitrile + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
oxime dervied from phenylalanine, 35% of the activity with (E)-4-hydroxyphenylacetaldehyde oxime
-
-
?
(Z)-3-methylbutanaloxime + [reduced NADPH-hemoprotein reductase] + O2
2-hydroxy-3-methylbutyronitrile + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
-
-
-
-
?
(Z)-4-hydroxyphenylacetaldehyde oxime
4-hydroxyphenylacetonitrile + H2O
show the reaction diagram
-
-
-
?
2-hydroxy(p-hydroxyphenyl)acetaldoxime
4-hydroxymandelonitrile + H2O
show the reaction diagram
-
poor substrate
-
-
?
4-hydroxyphenylacetonitrile + [reduced NADPH-hemoprotein reductase] + O2
(S)-4-hydroxymandelonitrile + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
L-tyrosine + 2 O2 + 2 [reduced NADPH-hemoprotein reductase]
(E)-[4-hydroxyphenylacetaldehyde oxime] + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
show the reaction diagram
-
-
-
-
?
additional information
?
-