Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.14.32: 17alpha-hydroxyprogesterone deacetylase

This is an abbreviated version!
For detailed information about 17alpha-hydroxyprogesterone deacetylase, go to the full flat file.

Word Map on EC 1.14.14.32

Reaction

17alpha-hydroxypregnenolone
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
3beta-hydroxyandrost-5-en-17-one
+
acetate
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

17,20 lyase, 17-20 lyase, 17-alpha-hydroxylase/C17-20 lyase, 17-hydroxylase/C17,20-lyase, 17alpha-hydroxylase, 17alpha-hydroxylase-C(17,20)-lyase, 17alpha-hydroxylase-C17,20-lyase, 17alpha-hydroxylase/17,20 lyase, 17alpha-hydroxylase/17,20-lyase, 17alpha-hydroxylase/17,20-lyase cytochrome P450, 17alpha-hydroxylase/C(17,20)-lyase, 17alpha-hydroxylase/C17,20-lyase, 17alpha-hydroxyprogesterone aldolase, 17alpha-hydroxyprogesterone aldolase/17,20-lyase, 17alpha-lyase, Adrenal 17,20-lyase, aldolase, 17alpha-hydroxyprogesterone, C-17,20 lyase, C-17/C-20 lyase, C17(20) lyase, C17,20 lyase, C17,20-lyase, CYP17, CYP17A1, cytochrome P450 17, cytochrome P450 17A1, cytochrome P450 17alpha-hydroxylase/17,20-lyase, cytochrome p450 17alpha-hydroxylase/C(17,20)-lyase, cytochrome P450c17, EC 4.1.2.30, P-45017alpha, P450 17A1, P45017alpha, P450c17, P450c17-I, steroid 17alphahydroxylase/17,20-lyase, Steroid C17(20) lyase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.32 17alpha-hydroxyprogesterone deacetylase

Natural Substrates Products

Natural Substrates Products on EC 1.14.14.32 - 17alpha-hydroxyprogesterone deacetylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
17-hydroxy-5alpha-pregnan-3alpha-ol-20-one + [reduced NADPH-hemoprotein reductase] + O2
androsterone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
17alpha-hydroxy-5alpha-dihydroprogesterone + [reduced NADPH-hemoprotein reductase] + O2
5alpha-androstanedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
17alpha-Hydroxypregnenolone
Dehydroepiandrosterone + acetaldehyde
show the reaction diagram
17alpha-hydroxypregnenolone + AH2 + O2
dehydroepiandrosterone + acetate + A + H2O
show the reaction diagram
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
5alpha-dihydroprogesterone + [reduced NADPH-hemoprotein reductase] + O2
17alpha-hydroxy-5alpha-dihydroprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
5alpha-pregnan-3alpha-ol-20-one + [reduced NADPH-hemoprotein reductase] + O2
17-hydroxy-5alpha-pregnan-3alpha-ol-20-one + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
7-dehydro-17alpha-hydroxypregnenolone + AH2 + O2
7-dehydro-dehydroepiandrosterone + acetate + A + H2O
show the reaction diagram
7-dehydro-pregnenolone + AH2 + O2
7-dehydro-17alpha-hydroxy-pregnenolone + A + H2O
show the reaction diagram
-
-
-
?
7-dehydro-pregnenolone + AH2 + O2
7-dehydro-17alpha-hydroxypregnenolone + A + H2O
show the reaction diagram
7alpha-hydroxypregnenolone + [reduced NADPH-hemoprotein reductase] + O2
3beta-hydroxyandrost-5-en-17-one + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
17,20-lyase activity
-
-
?
pregnenolone + reduced acceptor + O2
17alpha-hydroxypregnenolone + oxidized acceptor + H2O
show the reaction diagram
-
i.e. pregn-5-en-3beta-ol-20-one
-
-
?
pregnenolone + [reduced NADPH-hemoprotein reductase] + O2
17alpha-hydroxypregnenolone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
progesterone + AH2 + O2
17alpha-hydroxyprogesterone + A + H2O
show the reaction diagram
progesterone + [reduced NADPH-hemoprotein reductase] + O2
17alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
additional information
?
-