1.14.14.30: isobutylamine N-monooxygenase
This is an abbreviated version!
For detailed information about isobutylamine N-monooxygenase, go to the full flat file.
Reaction
Synonyms
IBAH, isobutylamine N-hydroxylase, vlmH
ECTree
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Substrates Products
Substrates Products on EC 1.14.14.30 - isobutylamine N-monooxygenase
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REACTION DIAGRAM
n-butylamine + FADH2 + O2
N-(butyl)hydroxylamine + FAD + H2O
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-
87% of the activity with 2-methylpropanamine
-
?
propan-1-amine + FADH2 + O2
N-(propyl)hydroxylamine + FAD + H2O
-
-
125% of the activity with 2-methylpropanamine
-
?
N-(2-butyl)hydroxylamine + FAD + H2O
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-
39% of the activity with 2-methylpropanamine
-
?
2-butylamine + FADH2 + O2
N-(2-butyl)hydroxylamine + FAD + H2O
-
-
39% of the activity with 2-methylpropanamine
-
?
N-hydroxy-2-methylpropan-1-amine + FAD + H2O
-
-
-
-
?
2-methylpropanamine + FADH2 + O2
N-hydroxy-2-methylpropan-1-amine + FAD + H2O
-
-
-
-
?
N-hydroxy-2-methylpropan-1-amine + FMN + H2O
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-
-
-
?
2-methylpropanamine + FMNH2 + O2
N-hydroxy-2-methylpropan-1-amine + FMN + H2O
-
-
-
-
?
N-(benzyl)hydroxylamine + FAD + H2O
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-
61% of the activity with 2-methylpropanamine
-
?
benzylamine + FADH2 + O2
N-(benzyl)hydroxylamine + FAD + H2O
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-
61% of the activity with 2-methylpropanamine
-
?
?
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-
amine N-hydroxylase cannot carry out the reduction of the flavin cofactor. Rather, the reduced flavin is supplied by a separate flavin reductase. The mechanism for the hydroxylation is likely to proceed via the formation of a flavin 4a-hydroperoxide
-
-
?
additional information
?
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-
amine N-hydroxylase cannot carry out the reduction of the flavin cofactor. Rather, the reduced flavin is supplied by a separate flavin reductase. The mechanism for the hydroxylation is likely to proceed via the formation of a flavin 4a-hydroperoxide
-
-
?