1.14.14.26: 24-hydroxycholesterol 7alpha-hydroxylase

This is an abbreviated version!
For detailed information about 24-hydroxycholesterol 7alpha-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.26

Reaction

(24S)-cholest-5-ene-3beta,24-diol
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(24S)-cholest-5-ene-3beta,7alpha,24-triol
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

24-hydroxycholesterol 7alpha-monooxygenase, Cyp39a1, CYP39A1 oxysterol 7alpha-hydroxylase, oxysterol 7alpha-hydroxylase CYP39A1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.26 24-hydroxycholesterol 7alpha-hydroxylase

Substrates Products

Substrates Products on EC 1.14.14.26 - 24-hydroxycholesterol 7alpha-hydroxylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(24R)-cholest-5-ene-3beta,24-diol + NADPH + H+ + O2
(24R)-cholest-5-ene-3beta,7alpha,24-triol + NADP+ + H2O
show the reaction diagram