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1.14.14.24: vitamin D 25-hydroxylase

This is an abbreviated version!
For detailed information about vitamin D 25-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.24

Reaction

calciol
+
O2
 +
[reduced NADPH-hemoprotein reductase]
=
calcidiol
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

CYP2R1, CYP24A1, CYP2C11, CYP2D25, CYP2J3, CYP2R1, CYPIIJ3, Cytochrome P450 2C11, cytochrome P450 2J2, Cytochrome P450 2J3, cytochrome P450 2R1, EC 1.14.13.159, VDH, vitamin D 25-hydroxylase, vitamin D-25-hydroxylase, vitamin D2 25-hydroxylase, vitamin D3 25-hydroxylase, vitamin D3 hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.24 vitamin D 25-hydroxylase

Source Tissue

Source Tissue on EC 1.14.14.24 - vitamin D 25-hydroxylase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
low expression
Manually annotated by BRENDA team
high levels of CYP2R1 expression compared to healthy adjacent tissue
Manually annotated by BRENDA team
additional information