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1.14.14.102: N-methylcoclaurine 3'-monooxygenase

This is an abbreviated version!
For detailed information about N-methylcoclaurine 3'-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.102

Reaction

(S)-N-methylcoclaurine
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
(S)-3'-hydroxy-N-methylcoclaurine
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

(S)-methylcoclaurine-3'-hydroxylase, (S)-N-methylcoclaurine 3'-hydroxylase, (S)-N-methylcoclaurine-3'-hydroxylase, (S)-N-methylcoclaurine-3-hydroxylase, CYP80B, CYP80B1, CYP80B3, Cytochrome P450 80B1, Cytochrome P450 80B2, EC 1.14.13.71, LOC104585940, N-methylcoclaurine 3'-hydroxylase, NMCH

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.102 N-methylcoclaurine 3'-monooxygenase

Reference

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Reference on EC 1.14.14.102 - N-methylcoclaurine 3'-monooxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Pauli, H.H.; Kutchan, T.M.
Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis
Plant J.
13
793-801
1998
Eschscholzia californica
Manually annotated by BRENDA team
Huang, F.C.; Kutchan, T.M.
Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somniferum
Phytochemistry
53
555-564
2000
Papaver bracteatum, Papaver somniferum, Papaver rhoeas, Papaver orientale
Manually annotated by BRENDA team
Alcantara, J.; Bird, D.A.; Franceschi, V.R.; Facchini, P.J.
Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment
Plant Physiol.
138
173-183
2005
Papaver somniferum
Manually annotated by BRENDA team
Samanani, N.; Alcantara, J.; Bourgault, R.; Zulak, K.G.; Facchini, P.J.
The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy
Plant J.
47
547-563
2006
Papaver somniferum
Manually annotated by BRENDA team
Cho, H.Y.; Son, S.Y.; Rhee, H.S.; Yoon, S.Y.; Lee-Parsons, C.W.; Park, J.M.
Synergistic effects of sequential treatment with methyl jasmonate, salicylic acid and yeast extract on benzophenanthridine alkaloid accumulation and protein expression in Eschscholtzia californica suspension cultures
J. Biotechnol.
135
117-122
2008
Eschscholzia californica
Manually annotated by BRENDA team
Frick, S.; Kramell, R.; Kutchan, T.M.
Metabolic engineering with a morphine biosynthetic P450 in opium poppy surpasses breeding
Metab. Eng.
9
169-176
2007
Papaver somniferum
Manually annotated by BRENDA team
Zhou, J.; Peng, S.; Lei, N.; Liao, H.; Chen, F.
Molecular cloning and sequence analysis of (S)-N-methylcoclaurine-3'-hydroxylase gene in Coptis chinensis
Zhong Cao Yao
39
419-423
2008
Coptis chinensis (B2BF50)
-
Manually annotated by BRENDA team
Desgagne-Penix, I.; Facchini, P.
Systematic silencing of benzylisoquinoline alkaloid biosynthetic genes reveals the major route to papaverine in opium poppy
Plant J.
72
331-344
2012
Papaver somniferum
Manually annotated by BRENDA team
Yang, M.; Zhu, L.; Li, L.; Li, J.; Xu, L.; Fen, J.; Liu, Y.
Digital gene expression analysis provides insight into the transcript profile of the genes involved in aporphine alkaloid biosynthesis in lotus (Nelumbo nucifera)
Front. Plant Sci.
8
80
2017
Nelumbo nucifera (A0A1U7Z269)
Manually annotated by BRENDA team