1.14.13.7: phenol 2-monooxygenase (NADPH)

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For detailed information about phenol 2-monooxygenase (NADPH), go to the full flat file.

Word Map on EC 1.14.13.7

1.14.13.7

catechols

phenol-degrading

hydroxylases

2,3-dioxygenase

trichosporon

cutaneum

meta-cleavage

diiron

cresol

comamonas

2-hydroxymuconic

testosteroni

haldane

coke

radioresistens

carboxylate-bridged

meta-pathway

ortho-cleavage

methylococcus

cis,cis-muconate

coking

environmental protection

industry

synthesis

degradation

Reaction

Synonyms

DmpLNO, flavin containing monooxygenase, LmPH, Mph, MphN, multi-component phenol hydroxylase, multicomponent PH, multicomponent phenol hydroxylase, multicomponent phenol hydroxylase alpha subunit, NCgl2588, oxygenase, phenol 2-mono-, PHE, phenol hydroxylase, phenol o-hydroxylase, PHH, phhY, PHIND, PHO, PHR, single-component PH, SPH

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.7 phenol 2-monooxygenase (NADPH)

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Results	in table
4	Activating Compound
1301	AA Sequence
16	Application
1	CAS Registry Number
27	Cloned(Commentary)
55	Cofactor
4	Crystallization (Commentary)
1	Expression
4	General Information
5	General Stability
78	Inhibitors
22	Ki Value [mM]
57	KM Value [mM]
4	Localization
10	Metals/Ions
17	Molecular Weight [Da]
46	Natural Substrates/ Products (Substrates)
192	Organism
7	Pathway
9	PDB ID
17	pH Optimum
6	pH Range
1	pH Stability
3	pI Value
12	Protein Variants
18	Purification (Commentary)
3	Reaction
3	Reaction Type
97	Reference
15	Source Tissue
17	Specific Activity [micromol/min/mg]
4	Storage Stability
324	Substrates and Products (Substrate)
27	Subunits
171	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
3	Temperature Range [°C]
2	Temperature Stability [°C]
15	Turnover Number [1/s]

Turnover Number

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Turnover Number on EC 1.14.13.7 - phenol 2-monooxygenase (NADPH)

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0.95

2-Cresol

Pseudomonas stutzeri

25°C, recombinant enzyme

671421

0.125

2-xylene

Pseudomonas stutzeri

25°C, recombinant enzyme

671421

0.61

3-cresol

Pseudomonas stutzeri

25°C, recombinant enzyme

671421

0.77

4-Cresol

Pseudomonas stutzeri

25°C, recombinant enzyme

671421

0.1

Benzene

Pseudomonas stutzeri

25°C, recombinant enzyme

671421

1980

NADH

Acinetobacter radioresistens

oxygenase component PHO

658619

2.08 - 11.5

NADPH

Cutaneotrichosporon cutaneum

value depends on phenolic substrate

438783

0.286 - 1980

phenol

4 entries

0.15

Toluene

Pseudomonas stutzeri

25°C, recombinant enzyme

671421

4.5 - 13.2

various phenolic substrates

Cutaneotrichosporon cutaneum

438783

additional information

2 entries