1.14.13.64: 4-hydroxybenzoate 1-hydroxylase

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate 1-hydroxylase, go to the full flat file.

Reaction

Synonyms

4-hydroxybenzoate 1-hydroxylase, 4-hydroxybenzoate 1-hydroxylase (decarboxylating), 4-hydroxybenzoate 1-monooxygenase, 4HB1H, Cp_4HB1H, FAD-dependent 4-hydroxybenzoate hydroxylase, MNX1, Mnx1p, Oxygenase, 4-hydroxybenzoate 1-mono, PHBH, V1H, vanillate 1-hydroxylase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.64 4-hydroxybenzoate 1-hydroxylase

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Results	in table
1	AA Sequence
6	Application
1	CAS Registry Number
3	Cloned(Commentary)
17	Cofactor
10	General Information
7	Inhibitors
3	kcat/KM [mM/s]
18	KM Value [mM]
2	Localization
5	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
34	Organism
2	Pathway
5	pH Optimum
2	Posttranslational Modification
1	Protein Variants
3	Purification (Commentary)
3	Reaction
2	Reaction Type
12	Reference
2	Specific Activity [micromol/min/mg]
70	Substrates and Products (Substrate)
10	Subunits
26	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
17	Turnover Number [1/s]

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Reference on EC 1.14.13.64 - 4-hydroxybenzoate 1-hydroxylase

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REF.

AUTHORS

TITLE

JOURNAL

VOL.

PAGES

YEAR

ORGANISM (UNIPROT)

PUBMED ID

SOURCE

7427

van Berkel, W.J.H.; Eppink, M.H.M.; Middelhoven, W.J.; Vervoort, J.; Rietjens, I.M.C.M.

Catabolism of 4-hydroxybenzoate in Candida parapsilosis proceeds through initial oxidative decarboxylation by a FAD-dependent 4-hydroxybenzoate 1-hydroxylase

FEMS Microbiol. Lett.

121

207-216

1994

Candida parapsilosis, Candida parapsilosis CBS604

7926672

brenda

7428

Eppink, M.H.M.; Boeren, S.A.; Vervoort, J.; van Berkel, W.J.H.

Purification and properties of 4-hydroxybenzoate 1-hydroxylase (decarboxylating), a novel flavin adenine dinucleotide-dependent monooxygenase from Candida parapsilosis CBS604

J. Bacteriol.

179

6680-6687

1997

Candida parapsilosis, Candida parapsilosis CBS604

9352916

brenda

657498

Moonen, M.J.H.; Fraaije, M.W.; Rietjens, I.M.C.M.; Laane, C.; Van Berkel, W.J.H.

Flavoenzyme-catalyzed oxygenations and oxidations of phenolic compounds

Adv. Synth. Catal.

344

1023-1035

2002

Candida parapsilosis, Candida parapsilosis CBS604

-

brenda

728255

Holesova, Z.; Jakubkova, M.; Zavadiakova, I.; Zeman, I.; Tomaska, L.; Nosek, J.

Gentisate and 3-oxoadipate pathways in the yeast Candida parapsilosis: identification and functional analysis of the genes coding for 3-hydroxybenzoate 6-hydroxylase and 4-hydroxybenzoate 1-hydroxylase

Microbiology

157

2152-2163

2011

Candida parapsilosis

21474535

brenda

745691

Shen, X.; Wang, J.; Wang, J.; Chen, Z.; Yuan, Q.; Yan, Y.

High-level de novo biosynthesis of arbutin in engineered Escherichia coli

Metab. Eng.

42

52-58

2017

Candida parapsilosis, Candida parapsilosis (G8B709), Candida parapsilosis CBS604, Candida parapsilosis CBS604 (G8B709)

28583673

brenda

764036

Westphal, A.H.; Tischler, D.; van Berkel, W.J.H.

Natural diversity of FAD-dependent 4-hydroxybenzoate hydroxylases

Arch. Biochem. Biophys.

702

108820

2021

Candida parapsilosis, Candida parapsilosis CBS604

33684360

brenda

764953

Shang, Y.; Wei, W.; Zhang, P.; Ye, B.C.

Engineering Yarrowia lipolytica for enhanced production of arbutin

J. Agric. Food Chem.

68

1364-1372

2020

Yarrowia lipolytica

31903751

brenda

Entries 1 - 20 of 7

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