1.14.13.63: 3-hydroxyphenylacetate 6-hydroxylase
This is an abbreviated version!
For detailed information about 3-hydroxyphenylacetate 6-hydroxylase, go to the full flat file.
Reaction
Synonyms
3,4-dihydroxyphenylacetate 6-hydroxylase, 3-Hydroxyphenylacetate 6-monooxygenase, CYP504B, m-Hydroxyphenylacetate 6-hydroxylase, More, Oxygenase, 3-hydroxyphenylacetate 6-mono
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Substrates Products
Substrates Products on EC 1.14.13.63 - 3-hydroxyphenylacetate 6-hydroxylase
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REACTION DIAGRAM
3,4-dihydroxyphenylacetate + NAD(P)H + O2 + H+
2,4,5-trihydroxyphenylacetate + NAD(P)+ + H2O
3-Hydroxyphenylacetate + NAD(P)H + O2
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enzyme in the 3-hydroxyphenylacetate catabolism
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?
4-Hydroxyphenylacetate + NADH + O2
2,4-Dihydroxyphenylacetate + NAD+
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?
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20% of the activity with 3-hydroxyphenylacetate
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2-hydroxyphenoxyacetate + NADH + O2
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20% of the activity with 3-hydroxyphenylacetate
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?
2,5-dihydroxyphenylacetate + NAD(P)+ + H2O
low activity
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?
2-hydroxyphenylacetate + NAD(P)H + O2
2,5-dihydroxyphenylacetate + NAD(P)+ + H2O
low activity, step in the 2,5-dihydroxyphenylacetate, i.e.homogentisic acid, catabolic pathway, overview
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?
2-hydroxyphenylacetate + NAD(P)H + O2
2,5-dihydroxyphenylacetate + NAD(P)+ + H2O
low activity
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?
2-hydroxyphenylacetate + NAD(P)H + O2
2,5-dihydroxyphenylacetate + NAD(P)+ + H2O
low activity, step in the 2,5-dihydroxyphenylacetate, i.e.homogentisic acid, catabolic pathway, overview
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-
?
2,4,5-trihydroxyphenylacetate + NAD(P)+ + H2O
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?
3,4-dihydroxyphenylacetate + NAD(P)H + O2
2,4,5-trihydroxyphenylacetate + NAD(P)+ + H2O
step in the 2,5-dihydroxyphenylacetate, i.e.homogentisic acid, catabolic pathway, overview
the product is a substrate for homogentisate dioxygenase
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?
3,4-dihydroxyphenylacetate + NAD(P)H + O2
2,4,5-trihydroxyphenylacetate + NAD(P)+ + H2O
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-
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?
3,4-dihydroxyphenylacetate + NAD(P)H + O2
2,4,5-trihydroxyphenylacetate + NAD(P)+ + H2O
step in the 2,5-dihydroxyphenylacetate, i.e.homogentisic acid, catabolic pathway, overview
the product is a substrate for homogentisate dioxygenase
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?
2,4,5-trihydroxyphenylacetate + NAD(P)+ + H2O
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-
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?
3,4-dihydroxyphenylacetate + NAD(P)H + O2 + H+
2,4,5-trihydroxyphenylacetate + NAD(P)+ + H2O
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?
2,4,5-Trihydroxyphenylacetate + NAD+
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?
3,4-Dihydroxyphenylacetate + NADH + O2
2,4,5-Trihydroxyphenylacetate + NAD+
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?
2,5-dihydroxyphenylacetate + NAD(P)+ + H2O
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?
3-hydroxyphenylacetate + NAD(P)H + O2
2,5-dihydroxyphenylacetate + NAD(P)+ + H2O
step in the 2,5-dihydroxyphenylacetate, i.e.homogentisic acid, catabolic pathway, overview
the product is a substrate for homogentisate dioxygenase
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?
3-hydroxyphenylacetate + NAD(P)H + O2
2,5-dihydroxyphenylacetate + NAD(P)+ + H2O
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?
2,5-Dihydroxyphenylacetate + NAD+
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NADPH and NADH are oxidized at a comparable rate
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?
3-Hydroxyphenylacetate + NADH + O2
2,5-Dihydroxyphenylacetate + NAD+
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NADPH and NADH are oxidized at a comparable rate
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?
3-Hydroxyphenylacetate + NADH + O2
2,5-Dihydroxyphenylacetate + NAD+
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?
3-Hydroxyphenylacetate + NADH + O2
2,5-Dihydroxyphenylacetate + NAD+
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enables growth on 3-hydroxyphenylacetate as sole carbon source
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3-Hydroxyphenylacetate + NADH + O2
2,5-Dihydroxyphenylacetate + NAD+
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?
3-Hydroxyphenylacetate + NADH + O2
2,5-Dihydroxyphenylacetate + NAD+
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enables growth on 3-hydroxyphenylacetate as sole carbon source
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?
2,5-Dihydroxyphenylacetate + NADP+
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NADPH and NADH are oxidized at a comparable rate
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?
3-Hydroxyphenylacetate + NADPH + O2
2,5-Dihydroxyphenylacetate + NADP+
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NADPH and NADH are oxidized at a comparable rate
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?
?
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in the absence of oxygen the free enzyme is slowly reduced by NADPH or NADH
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additional information
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in the absence of oxygen the free enzyme is slowly reduced by NADPH or NADH
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?