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1.14.13.244: phenol 2-monooxygenase (NADH)

This is an abbreviated version!
For detailed information about phenol 2-monooxygenase (NADH), go to the full flat file.

Reaction

phenol
+
NADH
+
H+
+
O2
=
catechol
+
NAD+
+
H2O

Synonyms

dmpLMNOP, DmpM, PheA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.244 phenol 2-monooxygenase (NADH)

Systematic Name

Systematic Name on EC 1.14.13.244 - phenol 2-monooxygenase (NADH)

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SYSTEMATIC NAME
IUBMB Comments
phenol,NADH:oxygen oxidoreductase (2-hydroxylating)
The enzyme, characterized from the bacteria Pseudomonas sp. CF600 and Acinetobacter radioresistens, consists of a multisubunit oxygenease component that contains the active site and a dinuclear iron center, a reductase component that contains FAD and one iron-sulfur cluster, and a regulatory component. The reductase component is responsible for transferring electrons from NADH to the dinuclear iron center.