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1.14.13.240: 2-polyprenylphenol 6-hydroxylase

This is an abbreviated version!
For detailed information about 2-polyprenylphenol 6-hydroxylase, go to the full flat file.

Reaction

2-(all-trans-polyprenyl)phenol
+
NADPH
+
H+
+
O2
=
3-(all-trans-polyprenyl)benzene-1,2-diol
+
NADP+
+
H2O

Synonyms

2-octaprenylphenol hydroxylase, HMPREF0602_0026, ubiI, ubiM, visC

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.240 2-polyprenylphenol 6-hydroxylase

Engineering

Engineering on EC 1.14.13.240 - 2-polyprenylphenol 6-hydroxylase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
G301A/N303A
mutation of residues form the bottom of the isoalloxazine binding pocket, strongly impairs UbiI activity