1.14.13.238: dimethylamine monooxygenase
This is an abbreviated version!
For detailed information about dimethylamine monooxygenase, go to the full flat file.
Word Map on EC 1.14.13.238
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1.14.13.238
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heme
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prosthetic
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axial
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ferric
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trimethylamine
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flavin
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protoporphyrin
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aminovorans
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myoglobin
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heme-containing
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myoglobin-like
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oxygenases
- 1.14.13.238
- heme
-
prosthetic
-
axial
-
ferric
- trimethylamine
- flavin
- protoporphyrin
- aminovorans
- myoglobin
-
heme-containing
-
myoglobin-like
- oxygenases
Reaction
Synonyms
dimethylamine mono-oxygenase, dmmABC, secondary amine mono-oxygenase, secondary amine monooxygenase
ECTree
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Substrates Products
Substrates Products on EC 1.14.13.238 - dimethylamine monooxygenase
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REACTION DIAGRAM
dipropylamine + NADH + H+ + O2
propylamine + acetaldehyde + NAD+ + H2O
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?
ethyl-n-propylamine + NADH + H+ + O2
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22% activity compared to dimethylamine
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-
?
ethylamine + NADH + H+ + O2
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65% activity compared to dimethylamine
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-
?
methyl-n-propylamine + NADH + H+ + O2
?
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87% activity compared to dimethylamine
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-
?
n-butylmethylamine + NADH + H+ + O2
?
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54% activity compared to dimethylamine
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?
n-methylethanolamine + NADH + H+ + O2
?
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19% activity compared to dimethylamine
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?
butylamine + acetaldehyde + NAD+ + H2O
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?
dibutylamine + NADH + H+ + O2
butylamine + acetaldehyde + NAD+ + H2O
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-
-
-
?
ethylamine + acetaldehyde + NAD+ + H2O
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40% activity compared to dimethylamine
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-
?
diethylamine + NADH + H+ + O2
ethylamine + acetaldehyde + NAD+ + H2O
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-
-
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?
diethylamine + NADH + H+ + O2
ethylamine + acetaldehyde + NAD+ + H2O
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-
-
-
?
methylamine + formaldehyde + NAD+ + H2O
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100% activity
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?
dimethylamine + NADH + H+ + O2
methylamine + formaldehyde + NAD+ + H2O
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-
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?
dimethylamine + NADH + H+ + O2
methylamine + formaldehyde + NAD+ + H2O
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-
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?
methylamine + formaldehyde + NADP+ + H2O
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?
dimethylamine + NADPH + H+ + O2
methylamine + formaldehyde + NADP+ + H2O
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good substrate
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-
?
dimethylamine + NADPH + H+ + O2
methylamine + formaldehyde + NADP+ + H2O
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?
dimethylamine + NADPH + H+ + O2
methylamine + formaldehyde + NADP+ + H2O
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?
dimethylamine + NADPH + H+ + O2
methylamine + formaldehyde + NADP+ + H2O
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?
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no activity with methylamine, ethylamine, n-propylamine, ethanolamine, aniline, 1,2-diaminopropane, 1,3-diaminopropane, di-isopropylamine, di-n-propylamine, di-isobutylamine, di-n-butylamine, diethanolamine, methyl-n-octylamine, N-methylaniline, benzylmethylamine, putrescine, spermidine, piperidine, sarcosine, N-methylglutamate, noradrenaline, trimethylamine, triethylamine, N,N-dimethylaniline, tetramethylammonium chloride, and tetraethylammonium chloride
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additional information
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no activity with methylamine, methanol or formaldehyde. The partially purified enzyme shows no significant activity with primary, tertiary and quaternary amines, nor with sarcosine
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?