1.14.13.235: indole-3-acetate monooxygenase

This is an abbreviated version!
For detailed information about indole-3-acetate monooxygenase, go to the full flat file.

Reaction

(indol-3-yl)acetate
+
NADH
+
H+
+
O2
=
(2-hydroxy-1H-indol-3-yl)acetate
+
NAD+
+
H2O

Synonyms

iacA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.235 indole-3-acetate monooxygenase

Systematic Name

Systematic Name on EC 1.14.13.235 - indole-3-acetate monooxygenase

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SYSTEMATIC NAME
IUBMB Comments
(indol-3-yl)acetate,NADH:oxygen oxidoreductase (2-hydroxylating)
The enzyme, characterized from Pseudomonas putida strains, catalyses the first step in a pathway for degradation of the plant hormone indole-3-acetate. When acting on indole, the enzyme forms indoxyl, which reacts spontaneously with oxygen to form the blue dye indigo.