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1.14.13.233: 4-hydroxy-6-methylpretetramide 12a-monooxygenase

This is an abbreviated version!
For detailed information about 4-hydroxy-6-methylpretetramide 12a-monooxygenase, go to the full flat file.

Reaction

4-hydroxy-6-methylpretetramide
+
NADPH
+
H+
+
O2
=
4-de(dimethylamino)-4-oxoanhydrotetracycline
+
NADP+
+
H2O

Synonyms

oxyL

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.233 4-hydroxy-6-methylpretetramide 12a-monooxygenase

Natural Substrates Products

Natural Substrates Products on EC 1.14.13.233 - 4-hydroxy-6-methylpretetramide 12a-monooxygenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
4-hydroxy-6-methylpretetramide + NADPH + H+ + O2
4-de(dimethylamino)-4-oxoanhydrotetracycline + NADP+ + H2O
show the reaction diagram