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1.14.13.223: 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase

This is an abbreviated version!
For detailed information about 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase, go to the full flat file.

Reaction

3-hydroxy-4-methylanthranilyl-[aryl-carrier protein]
+
NADH
+
H+
+
O2
=
3,5-dihydroxy-4-methylanthranilyl-[aryl-carrier protein]
+
NAD+
+
H2O

Synonyms

sibG

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.223 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase

Reference

Reference on EC 1.14.13.223 - 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Giessen, T.W.; Kraas, F.I.; Marahiel, M.A.
A four-enzyme pathway for 3,5-dihydroxy-4-methylanthranilic acid formation and incorporation into the antitumor antibiotic sibiromycin
Biochemistry
50
5680-5692
2011
Streptosporangium sibiricum (C0LTM1)
Manually annotated by BRENDA team