1.14.13.22: cyclohexanone monooxygenase

This is an abbreviated version!
For detailed information about cyclohexanone monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.22

1.14.13.22

baeyer-villiger

acinetobacter

lactones

bvmos

ncimb

calcoaceticus

cyclohexanol

synthesis

criegee

epsilon-caprolactone

c4a-peroxyflavin

biooxidation

bicyclo3.2.0hept-2-en-6-one

phenylacetone

cyclopentanone

biotechnology

Reaction

Synonyms

Bpro_556, CAMO, CHMO, ChnB, chnB protein, chnB1 protein, CHXON, CMO, cycloalkaone monooxygenase, cyclohexanone 1, 2-mono-oxygenase, cyclohexanone mono-oxygenase, cyclohexanone monooxygenase, cyclohexanone oxygenase, cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming), oxygenase, cyclohexanone mono-

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.22 cyclohexanone monooxygenase

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Results	in table
3	Activating Compound
667	AA Sequence
23	Application
2	CAS Registry Number
33	Cloned(Commentary)
84	Cofactor
5	Crystallization (Commentary)
3	General Information
1	General Stability
37	Inhibitors
30	kcat/KM [mM/s]
11	Ki Value [mM]
102	KM Value [mM]
6	Localization
1	Metals/Ions
16	Molecular Weight [Da]
51	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
171	Organism
1	Oxidation Stability
5	Pathway
14	PDB ID
15	pH Optimum
4	pH Range
6	pH Stability
59	Protein Variants
32	Purification (Commentary)
23	Reaction
11	Reaction Type
102	Reference
2	Source Tissue
28	Specific Activity [micromol/min/mg]
10	Storage Stability
491	Substrates and Products (Substrate)
16	Subunits
65	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
15	Temperature Stability [°C]
72	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.14.13.22 - cyclohexanone monooxygenase

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1,3-dithiane

Acinetobacter calcoaceticus

substrate inhibition

659743

2-Thiacyclohexanone

Acinetobacter sp.

substrate inactivates enzyme after a few turnovers

438973

2-Thiocyclohexanone

Acinetobacter sp.

438973

5,5'-dithiobis(2-nitrobenzoate)

5-deaza-FAD

competitive

arsenate

Bathocuproine

Cu2+

completely

CuCl2

cyclohexanone

Acinetobacter calcoaceticus

substrate inhibition

684613

delta-thiovalerolactone

Acinetobacter sp.

substrate inactivates enzyme after a few turnovers

diethyl dicarbonate

complete inhibition

EDTA

ethylene monothiocarbonate

Acinetobacter sp.

substrate inactivates enzyme after a few turnovers

FeCl3

iodoacetamide

NADP+

p-hydroxymercuribenzoate

Quinacrine

Quinine

S-gamma-Thiobutyrolactone

Acinetobacter sp.

substrate inactivates enzyme after a few turnovers

438973

additional information

3 entries