1.14.13.211: rifampicin monooxygenase This is an abbreviated version! For detailed information about rifampicin monooxygenase, go to the full flat file .
Reaction
rifampicin +
NAD(P)H +
O2 =
2'-N-hydroxyrifampicin +
NAD(P)+ +
H2O
Synonyms RIF-O, rifampicin monooxygenase, RifMO, rox
ECTree
Systematic Name
Systematic Name on EC 1.14.13.211 - rifampicin monooxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
rifampicin:NAD(P)H:oxygen oxidoreductase (2'-N-hydroxyrifampicin-forming)
The enzyme has been found in the Corynebacteria Rhodococcus equi and Nocardia farcinica. It confers increased resistance to the antibiotic rifampicin by initiating its degradation.