1.14.13.200: tetracenomycin A2 monooxygenase-dioxygenase

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For detailed information about tetracenomycin A2 monooxygenase-dioxygenase, go to the full flat file.

+ 2 O2 + 2 NAD(P)H + 2 H+ =

+ 2 NAD(P)+ +

ElmG, Tcm A2 oxygenase, Tcm B2 oxygenase, TcmG, tetracenomycin A2 oxygenase

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Results	in table
8	AA Sequence
5	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
1	General Information
3	KM Value [mM]
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
10	Organism
7	Pathway
2	pH Optimum
1	pH Range
1	pI Value
1	Purification (Commentary)
4	Reaction
8	Reference
1	Specific Activity [micromol/min/mg]
8	Substrates and Products (Substrate)
3	Subunits
8	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products on EC 1.14.13.200 - tetracenomycin A2 monooxygenase-dioxygenase

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tetracenomycin A2 + 2 O2 + 2 NAD(P)H + 2 H+

tetracenomycin C + 2 NAD(P)+ + H2O

biosynthesis tetracenomycin C, a polyketide antitumor antibiotic

tetracenomycin B2 + 2 O2 + 2 NAD(P)H + 2 H+

8-demethyl tetracenomycin C + 2 NAD(P)+ + H2O