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1.14.13.200: tetracenomycin A2 monooxygenase-dioxygenase

This is an abbreviated version!
For detailed information about tetracenomycin A2 monooxygenase-dioxygenase, go to the full flat file.

Reaction

tetracenomycin A2
+ 2 O2 + 2 NAD(P)H + 2 H+ =
tetracenomycin C
+ 2 NAD(P)+ +
H2O

Synonyms

ElmG, Tcm A2 oxygenase, Tcm B2 oxygenase, TcmG, tetracenomycin A2 oxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase

General Information

General Information on EC 1.14.13.200 - tetracenomycin A2 monooxygenase-dioxygenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
enzyme is responsible for the hydroxylation of tetracenomycin A2 at positions C-4, C-4a, and C-12a to give tetracenomycin C, i.e. the final step in tetracenomycin C biosynthesis