1.14.13.195: L-ornithine N5-monooxygenase (NADPH)
This is an abbreviated version!
For detailed information about L-ornithine N5-monooxygenase (NADPH), go to the full flat file.
Word Map on EC 1.14.13.195
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1.14.13.195
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flavin
-
fumigatus
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aspergillus
-
flavin-dependent
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pyoverdine
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nadp+
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c4a-hydroperoxyflavin
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hydroxamate
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hydroxamate-containing
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flavin-containing
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non-ribosomal
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half-reaction
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n-hydroxylating
- 1.14.13.195
- flavin
- fumigatus
- aspergillus
-
flavin-dependent
-
pyoverdine
- nadp+
-
c4a-hydroperoxyflavin
- hydroxamate
-
hydroxamate-containing
-
flavin-containing
-
non-ribosomal
-
half-reaction
-
n-hydroxylating
Reaction
Synonyms
Af-OMO, CchB, flavin-dependent monooxygenase, L-Orn N5-oxygenase, L-ornithine N5-hydroxylase, L-ornithine-Ndelta-oxygenase, monooxygenase EtcB, omega-amino acid monooxygenase, ornithine hydroxylase, ornithine N5-monooxygenase, PsbA, PvdA, SidA, siderophore A
ECTree
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Reference
Reference on EC 1.14.13.195 - L-ornithine N5-monooxygenase (NADPH)
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Putignani, L.; Ambrosi, C.; Ascenzi, P.; Visca, P.
Expression of L-ornithine Ndelta-oxygenase (PvdA) in fluorescent Pseudomonas species: an immunochemical and in silico study
Biochem. Biophys. Res. Commun.
313
245-257
2004
Burkholderia cepacia, Pseudomonas putida, Pseudomonas fluorescens, Ralstonia solanacearum, Pseudomonas syringae, Pseudomonas aeruginosa (Q51548), Pseudomonas aeruginosa
Meneely, K.M.; Lamb, A.L.
Biochemical characterization of a flavin adenine dinculeotide-dependent monooxygenase, ornithine hydroxylase from Pseudomonas aeruginosa, suggests a novel reaction mechanism
Biochemistry
46
11930-11937
2007
Pseudomonas aeruginosa
Meneely, K.M.; Barr, E.W.; Bollinger, J.M. Jr.; Lamb, A.L.
Kinetic mechanism of ornithine hydroxylase (PvdA) from Pseudomonas aeruginosa: substrate triggering of O2 addition but not flavin reduction
Biochemistry
48
4371-4376
2009
Pseudomonas aeruginosa
Ambrosi, C.; Leoni, L.; Putignani, L.; Orsi, N.; Visca, P.
Pseudobactin biogenesis, in the plant growth-promoting rhizobacterium Pseudomonas strain B10: Identification and functional analysis of the L-ornithine N5-oxygenase (psbA) gene
J. Bacteriol.
182
6233-6238
2000
Pseudomonas sp. (Q9F8X0), Pseudomonas sp. B10 (Q9F8X0)
Ge, L.; Seah, S.Y.K.
Heterologous expression, purification, and characterization of an L-ornithine N5-hydroxylase involved in pyoverdine siderophore biosynthesis in Pseudomonas aeruginosa
J. Bacteriol.
188
7205-7210
2006
Pseudomonas aeruginosa
Imperi, F.; Putignani, L.; Tiburzi, F.; Ambrosi, C.; Cipollone, R.; Ascenzi, P.; Visca, P.
Membrane-association determinants of the omega-amino acid monooxygenase PvdA, a pyoverdine biosynthetic enzyme from Pseudomonas aeruginosa
Microbiology
154
2804-2813
2008
Pseudomonas aeruginosa
Pohlmann, V.; Marahiel, M.A.
delta-Amino group hydroxylation of L-ornithine during coelichelin biosynthesis
Org. Biomol. Chem.
6
1843-1848
2008
Streptomyces coelicolor, Streptomyces coelicolor A3(2)
Robbel, L.; Helmetag, V.; Knappe, T.A.; Marahiel, M.A.
Consecutive enzymatic modification of ornithine generates the hydroxamate moieties of the siderophore erythrochelin
Biochemistry
50
6073-6080
2011
Saccharopolyspora erythraea
Romero, E.; Fedkenheuer, M.; Chocklett, S,W.; Qi, J.; Oppenheimer, M.; Sobrado, P.
Dual role of NADP(H) in the reaction of a flavin dependent N-hydroxylating monooxygenase
Biochim. Biophys. Acta
1824
850-857
2012
Aspergillus fumigatus (Q5SE95), Aspergillus fumigatus
Guillon, L.; El Mecherki, M.; Altenburger, S.; Graumann, P.L.; Schalk, I.J.
High cellular organization of pyoverdine biosynthesis in Pseudomonas aeruginosa: clustering of PvdA at the old cell pole
Environ. Microbiol.
14
1982-1994
2012
Pseudomonas aeruginosa
Frederick, R.E.; Mayfield, J.A.; DuBois, J.L.
Regulated O2 activation in flavin-dependent monooxygenases
J. Am. Chem. Soc.
133
12338-12341
2011
Aspergillus fumigatus
Olucha, J.; Meneely, K.M.; Chilton, A.S.; Lamb, A.L.
Two structures of an N-hydroxylating flavoprotein monooxygenase: ornithine hydroxylase from Pseudomonas aeruginosa
J. Biol. Chem.
286
31789-31798
2011
Pseudomonas aeruginosa (Q51548), Pseudomonas aeruginosa
Shirey, C.; Badieyan, S.; Sobrado, P.
Role of Ser-257 in the sliding mechanism of NADP(H) in the reaction catalyzed by the Aspergillus fumigatus flavin-dependent ornithine N5-monooxygenase SidA
J. Biol. Chem.
288
32440-32448
2013
Aspergillus fumigatus (Q5SE95), Aspergillus fumigatus
Badieyan, S.; Bach, R.; Sobrado, P.
Mechanism of N-hydroxylation catalyzed by flavin-dependent monooxygenases
J. Org. Chem.
80
2139-2147
2015
Aspergillus fumigatus (E9QYP0), Aspergillus fumigatus Af293 (E9QYP0)
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