1.14.13.182: 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

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For detailed information about 2-heptyl-3-hydroxy-4(1H)-quinolone synthase, go to the full flat file.

Reaction

Synonyms

2-heptyl-3,4-dihydroxyquinoline synthase, Aqm, PqsH

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.182 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

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Results	in table
47	AA Sequence
5	Cloned(Commentary)
3	Cofactor
2	Expression
1	General Information
9	kcat/KM [mM/s]
9	KM Value [mM]
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
10	Organism
5	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
10	Reference
1	Storage Stability
32	Substrates and Products (Substrate)
1	Subunits
10	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
9	Turnover Number [1/s]

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General Information on EC 1.14.13.182 - 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

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physiological function

Pseudomonas aeruginosa

Q9I0Q0

PqsH catalyzes the terminal step in biosynthesis of the Pseudomonas quinolone signal molecule 2-heptyl-3,4-dihydroxyquinoline. Under anaerobic conditions 2-heptyl-3-hydroxy-4(1H)-quinolone is not produced. The enzyme is a biochemical regulator of Pseudomonas Quinolone Signal controlled social behaviors in Pseudomonas aeruginosa

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