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1.14.13.172: salicylate 5-hydroxylase

This is an abbreviated version!
For detailed information about salicylate 5-hydroxylase, go to the full flat file.

Word Map on EC 1.14.13.172

Reaction

salicylate
+
NADH
+
H+
+
O2
=
2,5-Dihydroxybenzoate
+
NAD+
+
H2O

Synonyms

nagG, NagGH, nagH, S5H, S5HR, SAL5H, SalABCD, SALD

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.172 salicylate 5-hydroxylase

Systematic Name

Systematic Name on EC 1.14.13.172 - salicylate 5-hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
salicylate,NADH:oxygen oxidoreductase (5-hydroxylating)
This enzyme, which was characterized from the bacterium Ralstonia sp. U2, comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.7, ferredoxin---NAD(P)+ reductase), an iron-sulfur oxygenase, and ferredoxin.