1.14.13.149: phenylacetyl-CoA 1,2-epoxidase

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For detailed information about phenylacetyl-CoA 1,2-epoxidase, go to the full flat file.

Reaction

Synonyms

PaaABCDE, PaaABCE, PaaAC, PaaAC(D), phenylacetyl-CoA monooxygenase, ring 1,2 phenylacetyl-CoA epoxidase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.149 phenylacetyl-CoA 1,2-epoxidase

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Results	in table
1	Activating Compound
4620	AA Sequence
4	Cloned(Commentary)
4	Cofactor
2	Crystallization (Commentary)
9	General Information
1	General Stability
1	Inhibitors
3	KM Value [mM]
3	Metals/Ions
11	Organism
6	Pathway
1	PDB ID
1	pH Optimum
2	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
8	Reference
8	Substrates and Products (Substrate)
1	Subunits
13	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 1.14.13.149 - phenylacetyl-CoA 1,2-epoxidase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

epoxyphenylacetyl-CoA + O2 + NADPH + H+

?

2 entries

phenylacetyl-CoA + O2 + NADPH + H+

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+

4 entries

additional information

?

-

2 entries

epoxyphenylacetyl-CoA + O2 + NADPH + H+

?

Pseudomonas sp.

-

the di-iron center of PaaABCE also deoxygenates epoxyphenylacetyl-CoA, which occurs when phenylacetyl-CoA is largely used up

718163

-

-

?

epoxyphenylacetyl-CoA + O2 + NADPH + H+

?

Pseudomonas sp. Y2

-

the di-iron center of PaaABCE also deoxygenates epoxyphenylacetyl-CoA, which occurs when phenylacetyl-CoA is largely used up

718163

-

-

?

phenylacetyl-CoA + O2 + NADPH + H+

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+

Escherichia coli

-

-

716755

-

-

ir

phenylacetyl-CoA + O2 + NADPH + H+

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+

Escherichia coli

-

true substrate

717032

-

-

?

phenylacetyl-CoA + O2 + NADPH + H+

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+

Pseudomonas sp.

-

-

718163

-

-

?

phenylacetyl-CoA + O2 + NADPH + H+

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+

Pseudomonas sp. Y2

-

-

718163

-

-

?

additional information

?

-

Pseudomonas sp.

-

he non-physiological substrate benzoyl-CoA is not transformed to detectable products

718163

-

-

?

additional information

?

-

Pseudomonas sp. Y2

-

he non-physiological substrate benzoyl-CoA is not transformed to detectable products

718163

-

-

?