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1.14.13.149: phenylacetyl-CoA 1,2-epoxidase

This is an abbreviated version!
For detailed information about phenylacetyl-CoA 1,2-epoxidase, go to the full flat file.

Word Map on EC 1.14.13.149

Reaction

phenylacetyl-CoA
+
NADPH
+
H+
+
O2
=
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
+
NADP+
+
H2O

Synonyms

PaaABCDE, PaaABCE, PaaAC, PaaAC(D), phenylacetyl-CoA monooxygenase, ring 1,2 phenylacetyl-CoA epoxidase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.149 phenylacetyl-CoA 1,2-epoxidase

Reference

Reference on EC 1.14.13.149 - phenylacetyl-CoA 1,2-epoxidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Teufel, R.; Mascaraque, V.; Ismail, W.; Voss, M.; Perera, J.; Eisenreich, W.; Haehnel, W.; Fuchs, G.
Bacterial phenylalanine and phenylacetate catabolic pathway revealed
Proc. Natl. Acad. Sci. USA
107
14390-14395
2010
Escherichia coli
Manually annotated by BRENDA team
Grishin, A.; Ajamian, E.; Zhang, L.; Cygler, M.
Crystallization and preliminary X-ray analysis of PaaAC, the main component of the hydroxylase of the Escherichia coli phenylacetyl-coenzyme A oxygenase complex
Acta Crystallogr. Sect. F
66
1045-1049
2010
Escherichia coli
Manually annotated by BRENDA team
Grishin, A.; Ajamian, E.; Tao, L.; Zhang, L.; Menard, R.; Cygler, M.
Structural and functional studies of the Escherichia coli phenylacetyl-CoA monooxygenase complex
J. Biol. Chem.
286
10735-10743
2011
Escherichia coli (P76079), Escherichia coli
Manually annotated by BRENDA team
Teufel, R.; Friedrich, T.; Fuchs, G.
An oxygenase that forms and deoxygenates toxic epoxide
Nature
483
359-362
2012
Pseudomonas sp., Pseudomonas sp. Y2
Manually annotated by BRENDA team
Pribytkova, T.; Lightly, T.; Kumar, B.; Bernier, S.; Sorensen, J.; Surette, M.; Cardona, S.
The attenuated virulence of a Burkholderia cenocepacia paaABCDE mutant is due to inhibition of quorum sensing by release of phenylacetic acid
Mol. Microbiol.
94
522-536
2014
Burkholderia cenocepacia, Burkholderia cenocepacia K56-2
Manually annotated by BRENDA team
Lightly, T.; Frejuk, K.; Groleau, M.; Chiarelli, L.; Ras, C.; Buroni, S.; Deziel, E.; Sorensen, J.; Cardona, S.
Phenylacetyl coenzyme a, not phenylacetic acid, attenuates CepIR-regulated virulence in Burkholderia cenocepacia
Appl. Environ. Microbiol.
85
e01594
2019
Burkholderia cenocepacia (A0A1V6KKT5 and A0A125H2T4 and A0A2N9CKU5 and A0A088UAI6 and A0A7G6UV70), Burkholderia cenocepacia
Manually annotated by BRENDA team