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1.14.13.148: trimethylamine monooxygenase

This is an abbreviated version!
For detailed information about trimethylamine monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.148

Reaction

N,N,N-trimethylamine
+
NADPH
+
H+
+
O2
=
N,N,N-trimethylamine N-oxide
+
NADP+
+
H2O

Synonyms

dimethyl sulfoxide/trimethylamine N-oxide reductase, EC 1.14.13.8, FAD-containing monooxygenase, flavin containing monooxygenase 3, flavin monooxygenase 3, flavin-containing monooxygenase, flavin-containing monooxygenase 3, FMO, FMO3, FMO4, PB7211, TMA monooxygenase, TMA N-oxygenase, TMM

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.148 trimethylamine monooxygenase

Substrates Products

Substrates Products on EC 1.14.13.148 - trimethylamine monooxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
10-[(N,N-dimethylaminopentyl)]-2-(trifluoromethylphenothiazine) + NADPH + H+ + O2
?
show the reaction diagram
-
functional substrate
-
-
?
3-dimethylaminopropan-1-ol + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
3-dimethylaminopropan-2-ol + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
5-{[3-(dimethylamino)propyl]amino}-8-hydroxy-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one + NADPH + H+ + O2
5-{[3-(dimethylnitroryl)propyl]amino}-8-hydroxy-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one + NADP+ + H2O
show the reaction diagram
5-{[3-(dimethylamino)propyl]amino}-8-methoxy-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one + NADPH + H+ + O2
5-{[3-(dimethylnitroryl)propyl]amino}-8-methoxy-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one + NADP+ + H2O
show the reaction diagram
benzydamine + NADPH + H+ + O2
benzydamine N-oxide + NADP+ + H2O
show the reaction diagram
cysteamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
danusertib + NADPH + H+ + O2
danusertib N-oxide + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
diethylmethylamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
dimethyl sulfide + NADPH + H+ + O2
dimethyl sulfoxide + NADP+ + H2O
show the reaction diagram
-
-
-
?
dimethylaniline + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
dimethylsulfide + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
DMSO + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
ethionamide + NADPH + H+ + O2
ethionamide S-oxide + NADP+ + H2O
show the reaction diagram
ethyldimethylamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
methimazole + NADPH + H+ + O2
?
show the reaction diagram
methimazole + NADPH + H+ + O2
? + NADP+ + H2O
show the reaction diagram
-
-
-
?
methimazole + NADPH + H+ + O2
methimazole N-oxide + NADP+ + H2O
show the reaction diagram
methyl 4-tolyl sulfide + NADPH + H+ + O2
methyl 4-tolyl sulfoxide + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
N,N,N-trimethylamine + NADH + H+ + O2
N,N,N-trimethylamine N-oxide + NAD+ + H2O
show the reaction diagram
N,N,N-trimethylamine + NADPH + H+ + O2
N,N,N-trimethylamine N-oxide + NADP+ + H2O
show the reaction diagram
N,N-dimethyl-2-chloroethylamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
N,N-dimethylamine + NADPH + H+ + O2
N,N-dimethylamine N-oxide + NADP+ + H2O
show the reaction diagram
N,N-dimethylaniline + NADPH + H+ + O2
N,N-dimethylaniline N-oxide + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
N,N-dimethylbutylamine + NADPH + H+ + O2
N,N-dimethylbutylamine N-oxide + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
N,N-dimethylethanolamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
N,N-dimethylethylenediamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
N,N-dimethylpropylenediamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
sulindac sulfide + NADPH + H+ + O2
sulindac + NADP+ + H2O
show the reaction diagram
tozasertib + NADPH + H+ + O2
tozasertib N-oxide + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
triethylamine + NADPH + H+ + O2
?
show the reaction diagram
-
-
-
-
?
tyramine + NADPH + H+ + O2
4-[(2E)-2-(hydroxyimino)ethyl]phenol + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
additional information
?
-