1.14.13.148: trimethylamine monooxygenase

This is an abbreviated version!
For detailed information about trimethylamine monooxygenase, go to the full flat file.

Reaction

Synonyms

dimethyl sulfoxide/trimethylamine N-oxide reductase, EC 1.14.13.8, FAD-containing monooxygenase, flavin containing monooxygenase 3, flavin monooxygenase 3, flavin-containing monooxygenase, flavin-containing monooxygenase 3, FMO, FMO3, FMO4, PB7211, TMA monooxygenase, TMA N-oxygenase, TMM

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.148 trimethylamine monooxygenase

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Results	in table
4	Activating Compound
68	AA Sequence
12	Cloned(Commentary)
46	Cofactor
1	Crystallization (Commentary)
29	Disease/ Diagnostics
4	Expression
8	General Information
1	General Stability
22	Inhibitors
3	kcat/KM [mM/s]
46	KM Value [mM]
12	Localization
2	Metals/Ions
6	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
41	Organism
5	Pathway
4	pH Optimum
2	pH Range
1	pH Stability
1	Posttranslational Modification
24	Protein Variants
3	Purification (Commentary)
1	Reaction
3	Reaction Type
37	Reference
20	Source Tissue
5	Specific Activity [micromol/min/mg]
67	Substrates and Products (Substrate)
5	Subunits
77	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
4	Temperature Range [°C]
5	Temperature Stability [°C]
15	Turnover Number [1/s]

Purification

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Purification on EC 1.14.13.148 - trimethylamine monooxygenase

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PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

ammonium sulfate precipitation, Sephadex G-200 gel filtration, DEAE-cellulose column chromatography, and calcium phosphate chromatography

Calanus finmarchicus

-

717521

cholate solubilization and sequential column chromatography on octyl-Sepharose, DEAE-Sepharose, and hydroxyapatite

Homo sapiens

-

717530

DEAE ion exchange column chromatography and Ni affinity column chromatography

Homo sapiens

-

717229