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1.14.13.128: 7-methylxanthine demethylase

This is an abbreviated version!
For detailed information about 7-methylxanthine demethylase, go to the full flat file.

Word Map on EC 1.14.13.128

Reaction

7-methylxanthine
+
O2
+
NAD(P)H
+
H+
=
xanthine
+
NAD(P)+
+
H2O
+
formaldehyde

Synonyms

7-methylxanthine-specific N-demethylase, bacterial N-demethylase, caffeine demethylase, heteroxanthine demethylase, methylxanthine N-demethylase, N-demethylase, ndmA, NdmC, theobromine demethylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.128 7-methylxanthine demethylase

Cloned

Cloned on EC 1.14.13.128 - 7-methylxanthine demethylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21(DE3) cells
gene ndmA, recombinant expression of ndmA and ndmD genes in Escherichia coli
gene ndmC, genetic organization of caffeine-degrading genes and its isolation
gene ndmC, recombinant overexpression of His-tagged wild-type and mutant NdmC proteins, coexpression with NdmD and NdmE