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1.14.13.127: 3-(3-hydroxyphenyl)propanoate hydroxylase

This is an abbreviated version!
For detailed information about 3-(3-hydroxyphenyl)propanoate hydroxylase, go to the full flat file.

Reaction

(2E)-3-(3-hydroxyphenyl)prop-2-enoate
+
NADH
+
H+
+
O2
=
(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate
+
H2O
+
NAD+

Synonyms

3-(3-hydroxyphenyl)propionate hydroxylase, 3HPP 2-hydroxylase, 3HPP hydroxylase, MhpA, MhpAK-12

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.127 3-(3-hydroxyphenyl)propanoate hydroxylase

KCat KM Value

KCat KM Value on EC 1.14.13.127 - 3-(3-hydroxyphenyl)propanoate hydroxylase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.813
NADH
pH 7.4, 22°C, recombinant wild-type enzyme
1.684
NADPH
pH 7.4, 22°C, recombinant wild-type enzyme