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1.14.13.113: FAD-dependent urate hydroxylase

This is an abbreviated version!
For detailed information about FAD-dependent urate hydroxylase, go to the full flat file.

Reaction

Urate
+
NADH
+
H+
+
O2
=
5-hydroxyisourate
+
NAD+
+
H2O

Synonyms

FAD-dependent urate oxidase, flavin adenine dinucleotide-dependent urate oxidase, HpxO, HpxO enzyme, HpyO, urate hydroxylase, XCC0279

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.113 FAD-dependent urate hydroxylase

KM Value

KM Value on EC 1.14.13.113 - FAD-dependent urate hydroxylase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.024 - 0.64
NADH
0.055
NADPH
in 50 mM K2HPO4/NaH2PO4, pH 8.0, at 25°C
0.029 - 0.9
Urate