1.14.13.101: senecionine N-oxygenase

This is an abbreviated version!
For detailed information about senecionine N-oxygenase, go to the full flat file.

Reaction

senecionine
+
NADPH
+
H+
+
O2
=
senecionine N-oxide
+
NADP+
+
H2O

Synonyms

GgPNO, oxygenase, senecionine N-, PA N-oxygenase, PNO, senecionine monooxygenase (N-oxide-forming), senecionine N-oxygenase, SNO, TjSNO

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.101 senecionine N-oxygenase

KM Value

KM Value on EC 1.14.13.101 - senecionine N-oxygenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00983
atropine
-
in 100 mM glycine/NaOH buffer pH 9.0, at 37°C
0.0186 - 0.284
heliotrine
0.0029 - 0.0125
monocrotaline
0.0013
NADPH
-
pH 7.0, pH 37°C
0.8376
phalaenopsine
-
in 100 mM glycine/NaOH buffer pH 9.0, at 37°C
0.00108 - 0.0048
senecionine