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1.14.13.101: senecionine N-oxygenase

This is an abbreviated version!
For detailed information about senecionine N-oxygenase, go to the full flat file.

Reaction

senecionine
+
NADPH
+
H+
+
O2
=
senecionine N-oxide
+
NADP+
+
H2O

Synonyms

flavin-dependent monooxygenase, fmoa, GgPNO, oxygenase, senecionine N-, PA N-oxygenase, PNO, pyrrolizidine alkaloid N-oxygenase, senecionine monooxygenase (N-oxide-forming), senecionine N-oxygenase, SNO, TjSNO, ZvFMOa, ZvPNO

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.101 senecionine N-oxygenase

KCat KM Value

KCat KM Value on EC 1.14.13.101 - senecionine N-oxygenase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
37.64
atropine
-
in 100 mM glycine/NaOH buffer pH 9.0, at 37°C
0.454
heliotrine
-
in 100 mM glycine/NaOH buffer pH 9.0, at 37°C
80.5
monocrotaline
-
in 100 mM glycine/NaOH buffer pH 9.0, at 37°C
0.155
phalaenopsine
-
in 100 mM glycine/NaOH buffer pH 9.0, at 37°C
916.7
senecionine
-
in 100 mM glycine/NaOH buffer pH 9.0, at 37°C