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1.14.12.3: benzene 1,2-dioxygenase

This is an abbreviated version!
For detailed information about benzene 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.3

Reaction

Benzene
+
NADH
+
H+
+
O2
=
cis-cyclohexa-3,5-diene-1,2-diol
+
NAD+

Synonyms

BDO, BED, benzene dioxygenase, benzene hydroxylase, More, oxygenase, benzene 1,2-di-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.3 benzene 1,2-dioxygenase

Natural Substrates Products

Natural Substrates Products on EC 1.14.12.3 - benzene 1,2-dioxygenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
1-methylcyclohexene + O2 + NADH
?
show the reaction diagram
2 cyclohexene + 2 O2 + 2 NADH + 2 H+
2-cyclohexen-1-ol + cis-1,2-cyclohexanediol + 2 NAD+ + H2O
show the reaction diagram
-
-
failure of transformed bacteria to grow on cyclohexene is attributed to the toxicity of metabolic intermediates accumulating from the 2-cyclohexen-1-ol metabolism, cyclohexene metabolism pathways, overview
-
?
3-methylcyclohexene + O2 + NADH
?
show the reaction diagram
benzene + NADH + H+ + O2
cis-cyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
benzene + NADH + O2
(1R,2S)-cis-cyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
-
bioremediation of aromatic environmental pollutants, initial step of benzene degradation
-
-
?
benzene + NADH + O2
?
show the reaction diagram
benzene + O2 + NADH
cis-cyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
toluene + O2 + NADH
?
show the reaction diagram
-
-
-
-
?