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1.14.12.26: chlorobenzene dioxygenase

This is an abbreviated version!
For detailed information about chlorobenzene dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.26

Reaction

chlorobenzene
+
NADH
+
H+
+
O2
=
(1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol
+
NAD+

Synonyms

CDO, TecA, tetrachlorobenzene dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.26 chlorobenzene dioxygenase

Systematic Name

Systematic Name on EC 1.14.12.26 - chlorobenzene dioxygenase

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SYSTEMATIC NAME
IUBMB Comments
chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
This bacterial enzyme is a class IIB dioxygenase, comprising three components - a heterodimeric terminal dioxygenase, a ferredoxin protein, and a ferredoxin reductase. The enzyme acts on a range of aromatic compounds, including mono-, di-, tri-, and tetra-chlorinated benzenes and toluenes.