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1.14.12.26: chlorobenzene dioxygenase

This is an abbreviated version!
For detailed information about chlorobenzene dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.26

Reaction

chlorobenzene
+
NADH
+
H+
+
O2
=
(1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol
+
NAD+

Synonyms

CDO, TecA, tetrachlorobenzene dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.26 chlorobenzene dioxygenase

Substrates Products

Substrates Products on EC 1.14.12.26 - chlorobenzene dioxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1,2,4,5-tetrachlorobenzene + NADH + H+ + O2
? + NAD+
show the reaction diagram
1,2,4-trichlorobenzene + NADH + H+ + O2
? + NAD+
show the reaction diagram
-
-
-
-
?
1,3-dichlorobenzene + NADH + H+ + O2
? + NAD+
show the reaction diagram
-
-
-
-
?
1,4-dichlorobenzene + NADH + H+ + O2
? + NAD+
show the reaction diagram
1,4-dimethylbenzene + NADH + H+ + O2
? + NAD+
show the reaction diagram
-
oxidized with low efficiency
-
-
?
2,3-dichlorotoluene + NADH + H+ + O2
2,3-dichlorobenzyl alcohol + NAD+
show the reaction diagram
-
-
-
-
?
2,4,5-trichlorotoluene + NADH + H+ + O2
2,4,5-trichlorobenzyl alcohol + NAD+
show the reaction diagram
-
-
-
-
?
2,6-dichlorotoluene + NADH + H+ + O2
2,6-dichlorobenzyl alcohol + NAD+
show the reaction diagram
-
-
-
-
?
2-bromobenzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-4-bromo-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
2-chlorobenzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-4-chloro-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
2-fluorobenzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-4-fluoro-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
3,5-dichlorotoluene + NADH + H+ + O2
3,5-dichlorobenzyl alcohol + NAD+
show the reaction diagram
-
-
-
-
?
3-chlorobenzoate + NADH + H+ + O2
? + NAD+
show the reaction diagram
-
-
-
-
?
3-fluorobenzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-5-fluoro-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
4-chlorobenzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-6-chloro-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
4-fluorobenzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-6-fluoro-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
4-methylbenzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-6-methyl-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
benzonitrile + NADH + H+ + O2
cis-1,2-dihydroxy-3-cyanocyclohexa-3,5-diene + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
benzyl cyanide + NADH + H+ + O2
cis-1,2-dihydroxy-3,5-cyclohexadienyl acetonitrile + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
chlorobenzene + NADH + H+ + O2
(1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
cinnamonitrile + NADH + H+ + O2
trans-3-[(5S,6R)-5,6-dihydroxycyclo-hexa-1,3-dienyl]-acrylonitrile + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
cinnamonitrile + NADH + H+ + O2
trans-3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]-acrylonitrile + NAD+
show the reaction diagram
Q52383; Q52384; Q52385; Q52386
-
-
-
?
methylbenzene + NADH + H+ + O2
? + NAD+
show the reaction diagram
-
oxidized with low efficiency
-
-
?