1.14.11.9: flavanone 3-dioxygenase

This is an abbreviated version!
For detailed information about flavanone 3-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.9

1.14.11.9

chalcone

anthocyanins

dihydroflavonols

flavonols

anthocyanidin

4-reductase

ammonia-lyase

3\'-hydroxylase

petunia

proanthocyanidins

dihydrokaempferol

leucoanthocyanidin

3-o-glucosyltransferase

2-oxoglutarate-dependent

3',5'-hydroxylase

r2r3-myb

eriodictyol

analysis

testa

udp-glucose:flavonoid

2s-flavanones

4-coumarate-coa

dihydroflavonol-4-reductase

dihydroquercetin

2s-naringenin

pelargonidin

synthesis

agriculture

Reaction

Synonyms

(2S)-flavanone 3-hydroxylase, AaF3H, AcF3H, BnF3H, CsF3H, CtF3H, F3H, F3H protein, F3H1, F3H2, FHT, FHTPH, flavanone 3-dioxygenase, flavanone 3-hydroxylase, flavanone 3beta-hydroxylase, flavanone synthase I, flavanone-3-hydroxylase, FLS1, FLS2, FS I, LcF3H, naringenin 3-dioxygenase, naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating), oxygenase, flavanone 3-di-, PeF3H, PgF3H, PnF3H, RtF3H1, RtF3H2, VcF3H

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

1.14.11.9 flavanone 3-dioxygenase

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Results	in table
20	Activating Compound
247	AA Sequence
11	Application
1	CAS Registry Number
46	Cloned(Commentary)
24	Cofactor
16	Expression
38	General Information
61	Inhibitors
3	Ki Value [mM]
23	KM Value [mM]
11	Localization
26	Metals/Ions
14	Molecular Weight [Da]
62	Natural Substrates/ Products (Substrates)
105	Organism
1	Oxidation Stability
8	Pathway
18	pH Optimum
2	pH Range
6	pI Value
32	Protein Variants
20	Purification (Commentary)
2	Reaction
3	Reaction Type
90	Reference
133	Source Tissue
38	Specific Activity [micromol/min/mg]
1	Storage Stability
130	Substrates and Products (Substrate)
20	Subunits
152	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
2	Temperature Range [°C]
2	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 1.14.11.9 - flavanone 3-dioxygenase

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(+)-dihydrokaempferol

Petunia x hybrida

product inhibition

439119

3-Bromo-2-oxoglutarate

Petunia x hybrida

1 mM 92% inhibition

439119

3-hydroxy-5-oxo-4-butyryl-cyclohex-3-ene-1-carboxylic acid ethyl ester

2 entries

3-hydroxy-5-oxo-4-cyclopropanecarbonyl-cyclohex-3-ene-1-carboxylic acid ethyl ester

2 entries

3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-(2-dimethylamino)-thiazole

2 entries

3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-carbaldehyde

2 entries

3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-carbothioic acid S-ethyl ester

2 entries

3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-pentanoic acid

2 entries

benzene-1,2,4,5-tetracarboxylic acid

2 entries

calcium 3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-carboxylate

2 entries

Cu2+

2 entries

diethyldicarbonate

5 entries

diethyldithiocarbamate

EDTA

Fe3+

1 mM, 56% inhibition

KCN

p-chloromercuribenzoate

3 entries

prohexadione-Ca

Malus domestica

an enzyme inhibitor for 2-oxoglutarate dependent dioxygenases, used as a growth retardant and for control of secondary fire blight, Erwinia amylovora, of apple leaves

726200

Pyridine-2,4-dicarboxylate

2 entries

pyridine-2,4-dicarboxylic acid diethyl ester

2 entries

Pyridine-2,5-dicarboxylate

Petunia x hybrida

0.01 mM, 40% inhibition

439119

pyridine-2,5-dicarboxylic acid

2 entries

sodium 4,6-dioxo-2,2-dimethyl-5-(1-alloxyamino-butylidene)-cyclohexane-1-carboxylic acid methyl ester

2 entries

Zn2+

Petroselinum crispum

in presence of 0.01 mM Fe2+

439113