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1.14.11.78: (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase

This is an abbreviated version!
For detailed information about (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase, go to the full flat file.

Reaction

a (3R)-3-([carboxy(hydroxy)methyl]amino)fatty acid
+
2-oxoglutarate
+
O2
=
a (3R)-3-isocyanyl-fatty acid
+
succinate
+ 2 CO2 + 2 H2O

Synonyms

mmaE, Rv0097, Sav607, scoE, SfaA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.78 (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase

Reference

Reference on EC 1.14.11.78 - (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Li, H.; Liu, Y.
Mechanistic investigation of isonitrile formation catalyzed by the nonheme iron/alpha-KG-dependent decarboxylase (ScoE)
ACS Catal.
10
2942-2957
2020
Streptomyces coeruleorubidus (A0A3B6UEU3)
-
Manually annotated by BRENDA team
Harris, N.; Born, D.; Cai, W.; Huang, Y.; Martin, J.; Khalaf, R.; Drennan, C.; Zhang, W.
Isonitrile formation by a non-heme iron(II)-dependent oxidase/decarboxylase
Angew. Chem. Int. Ed. Engl.
57
9707-9710
2018
Streptomyces coeruleorubidus (A0A3B6UEU3)
Manually annotated by BRENDA team
Chen, T.; Chen, J.; Tang, Y.; Zhou, J.; Guo, Y.; Chang, W.
Pathway from N-alkylglycine to alkylisonitrile catalyzed by iron(II) and 2-oxoglutarate-dependent oxygenases
Angew. Chem. Int. Ed.Engl.
59
7367-7371
2020
Streptomyces avermitilis, Streptomyces thioluteus, Streptomyces coeruleorubidus (A0A3B6UEU3)
Manually annotated by BRENDA team
Del Rio Flores, A.; Kastner, D.; Du, Y.; Narayanamoorthy, M.; Shen, Y.; Cai, W.; Vennelakanti, V.; Zill, N.; Dell, L.; Zhai, R.; Kulik, H.; Zhang, W.
Probing the mechanism of isonitrile formation by a non-heme iron(II)-dependent oxidase/decarboxylase
J. Am. Chem. Soc.
144
5893-5901
2022
Streptomyces coeruleorubidus (A0A3B6UEU3)
Manually annotated by BRENDA team
Jonnalagadda, R.; Del Rio Flores, A.; Cai, W.; Mehmood, R.; Narayanamoorthy, M.; Ren, C.; Zaragoza, J.; Kulik, H.; Zhang, W.; Drennan, C.
Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/ decarboxylase
J. Biol. Chem.
296
100231
2021
Streptomyces coeruleorubidus (A0A3B6UEU3)
Manually annotated by BRENDA team
Harris, N.; Sato, M.; Herman, N.; Twigg, F.; Cai, W.; Liu, J.; Zhu, X.; Downey, J.; Khalaf, R.; Martin, J.; Koshino, H.; Zhang, W.
Biosynthesis of isonitrile lipopeptides by conserved nonribosomal peptide synthetase gene clusters in Actinobacteria
Proc. Natl. Acad. Sci. USA
114
7025-7030
2017
Mycobacterium marinum, Streptomyces coeruleorubidus (A0A3B6UEU3)
Manually annotated by BRENDA team
Ali, H.; Ghafoor, S.; de Visser, S.
Density functional theory study into the reaction mechanism of isonitrile biosynthesis by the nonheme iron enzyme ScoE
Top. Catal.
65
528-543
2022
Streptomyces coeruleorubidus (A0A3B6UEU3)
-
Manually annotated by BRENDA team