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1.14.11.74: L-isoleucine 31-dioxygenase

This is an abbreviated version!
For detailed information about L-isoleucine 31-dioxygenase, go to the full flat file.

Reaction

L-isoleucine
+
2-oxoglutarate
+
O2
=
31-hydroxy-L-isoleucine
+
succinate
+
CO2

Synonyms

HilA, L-isoleucine 4'-dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.74 L-isoleucine 31-dioxygenase

Substrates Products

Substrates Products on EC 1.14.11.74 - L-isoleucine 31-dioxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-isoleucine + 2-oxoglutarate + O2
(3S)-3'-hydroxy-L-isoleucine + succinate + CO2
show the reaction diagram
L-isoleucine + 2-oxoglutarate + O2
31-hydroxy-L-isoleucine + succinate + CO2
show the reaction diagram
L-methionine + 2-oxoglutarate + O2
L-methionine sulfoxide + succinate + CO2
show the reaction diagram
L-valine + 2-oxoglutarate + O2
4-hydroxy-L-valine + succinate + CO2
show the reaction diagram