1.14.11.73: [protein]-arginine 3-hydroxylase

This is an abbreviated version!
For detailed information about [protein]-arginine 3-hydroxylase, go to the full flat file.

Reaction

[protein]-L-arginine
+
2-oxoglutarate
+
O2
=
[protein]-(3R)-3-hydroxy-L-arginine
+
succinate
+
CO2

Synonyms

JMJD5, KDM8

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.73 [protein]-arginine 3-hydroxylase

Engineering

Engineering on EC 1.14.11.73 - [protein]-arginine 3-hydroxylase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
H321A
substitution of Fe2+-binding residue, significantly reduces 2-oxoglutarate turnover