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1.14.11.72: [2-(trimethylamino)ethyl]phosphonate dioxygenase

This is an abbreviated version!
For detailed information about [2-(trimethylamino)ethyl]phosphonate dioxygenase, go to the full flat file.

Reaction

[2-(trimethylamino)ethyl]phosphonate
+
2-oxoglutarate
 +
O2
=
[(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate
 +
succinate
 +
CO2

Synonyms

gamma-butyrobetaine hydroxylase, tmpA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.72 [2-(trimethylamino)ethyl]phosphonate dioxygenase

Substrates Products

Substrates Products on EC 1.14.11.72 - [2-(trimethylamino)ethyl]phosphonate dioxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-aminoethylphosphonate + 2-oxoglutarate + O2
?
show the reaction diagram
-
-
-
?
3-aminopropylphosphonate + 2-oxoglutarate + O2
?
show the reaction diagram
-
-
-
?
phosphocholine + 2-oxoglutarate + O2
glycine betaine aldehyde + phosphate + succinate + CO2
show the reaction diagram
-
-
-
?
[2-(dimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2
[(1R)-1-hydroxy-2-(dimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2
show the reaction diagram
-
-
-
?
[2-(trimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2
[(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + succinate + CO2
show the reaction diagram
-
-
-
?
additional information
?
-
no activity with gamma-butyrobetaine or analogue substrates
-
-
-