1.14.11.7: procollagen-proline 3-dioxygenase
This is an abbreviated version!
For detailed information about procollagen-proline 3-dioxygenase, go to the full flat file.
Word Map on EC 1.14.11.7
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1.14.11.7
-
hypoxia-inducible
-
fibrosis
-
hydroxyproline
-
factor-1
-
endothelial
-
hydroxylases
-
hif-1alpha
-
erythropoietin
-
anemia
-
domain-containing
-
lysyl
-
ascorbate
-
oxygen-dependent
-
normoxic
-
hippel-lindau
-
4-hydroxylase
-
imperfecta
-
osteogenesis
-
dmog
-
dimethyloxalylglycine
-
bleomycin
-
factor-1alpha
-
oxygen-sensing
-
angiogenic
-
2-oxoglutarate-dependent
-
hypoxia-responsive
-
chick-embryo
-
hif-dependent
-
hydroxylysine
-
hif-prolyl
-
roxadustat
-
o2-dependent
-
bleomycin-induced
-
ppib
-
polycythemia
-
fkbp10
-
intratracheal
-
3-hydroxylation
-
3,4-dihydroxybenzoic
-
prolyl-hydroxylase
-
hepcidin
-
oxygen-sensitive
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1.14.11.2
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hydroxyproline-rich
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col1a2
-
serpinh1
-
lindau
-
l-mimosine
-
erythropoiesis-stimulating
- 1.14.11.7
-
hypoxia-inducible
- fibrosis
- hydroxyproline
- factor-1
- endothelial
- hydroxylases
- hif-1alpha
- erythropoietin
- anemia
-
domain-containing
-
lysyl
- ascorbate
-
oxygen-dependent
-
normoxic
-
hippel-lindau
-
4-hydroxylase
- imperfecta
-
osteogenesis
- dmog
- dimethyloxalylglycine
- bleomycin
- factor-1alpha
-
oxygen-sensing
-
angiogenic
-
2-oxoglutarate-dependent
-
hypoxia-responsive
-
chick-embryo
-
hif-dependent
- hydroxylysine
-
hif-prolyl
-
roxadustat
-
o2-dependent
-
bleomycin-induced
- ppib
- polycythemia
- fkbp10
-
intratracheal
-
3-hydroxylation
-
3,4-dihydroxybenzoic
-
prolyl-hydroxylase
- hepcidin
-
oxygen-sensitive
-
1.14.11.2
-
hydroxyproline-rich
-
col1a2
-
serpinh1
-
lindau
- l-mimosine
-
erythropoiesis-stimulating
Reaction
Synonyms
LEPRE1, Leprel1, Leprel2, More, oxygenase, protocollagen proline 3-di-, P3H1, P3H2, P3H3, PHD3, proline,2-oxoglutarate 3-dioxygenase, prolyl 3-hydroxylase, prolyl 3-hydroxylase 1, prolyl 3-hydroxylase 2, prolyl 3-hydroxylase-2, prolyl hydroxylase, prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating, protocollagen proline 3-hydroxylase
ECTree
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Systematic Name
Systematic Name on EC 1.14.11.7 - procollagen-proline 3-dioxygenase
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[procollagen]-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
Requires Fe2+ and ascorbate. The enzyme forms a complex with protein disulfide isomerase, and is located in the endoplasmic reticulum. It modifies proline residues within the procollagen peptide of certain collagen types. The modification is essential for proper collagen triple helix formation.