1.14.11.65: [histone H3]-dimethyl-L-lysine9 demethylase
This is an abbreviated version!
For detailed information about [histone H3]-dimethyl-L-lysine9 demethylase, go to the full flat file.
Word Map on EC 1.14.11.65
-
1.14.11.65
-
dermal
-
stratum
-
corneum
-
permeation
-
uvb-induced
-
transdermal
-
keratinocytes
-
collagen
-
carcinogenesis
-
percutaneous
-
follicle
-
notch
-
erythema
-
solar
-
wrinkle
-
photoaging
-
transepidermal
-
guinea
-
hyperplasia
-
photocarcinogenesis
-
irritation
-
flap
-
dermatitis
-
iontophoresis
-
photodamage
-
alopecia
-
scalp
-
uvb-irradiated
-
photoprotective
-
propylene
-
cream
-
full-thickness
-
sunscreen
-
sunburn
-
tape
-
franz
-
demethylases
-
sebaceous
-
ointment
-
cyclobutane
-
dorsum
-
bald
-
8-methoxypsoralen
-
intracutaneous
-
nevus
-
microneedle
-
ultraviolet-induced
-
eyebrow
-
tranylcypromine
-
sencar
-
medicine
-
drug development
- 1.14.11.65
- dermal
-
stratum
- corneum
-
permeation
-
uvb-induced
-
transdermal
- keratinocytes
- collagen
- carcinogenesis
-
percutaneous
- follicle
- notch
- erythema
-
solar
-
wrinkle
-
photoaging
-
transepidermal
- guinea
- hyperplasia
-
photocarcinogenesis
-
irritation
- flap
- dermatitis
-
iontophoresis
-
photodamage
- alopecia
- scalp
-
uvb-irradiated
-
photoprotective
- propylene
-
cream
-
full-thickness
-
sunscreen
- sunburn
-
tape
-
franz
- demethylases
-
sebaceous
-
ointment
-
cyclobutane
- dorsum
-
bald
- 8-methoxypsoralen
-
intracutaneous
- nevus
-
microneedle
-
ultraviolet-induced
-
eyebrow
- tranylcypromine
-
sencar
- medicine
- drug development
Reaction
Synonyms
AOF2, AtJMJ17, BHC110, G9A/KMT1C, GLP/KMT1D, H3K4me2 demethylase, H3K9 demethylase, H3K9 histone demethylase, H3K9 Jumonji demethylase, H3K9 mono- and di-demethylase, H3K9Me2 demethylase, H3K9me2 methylase, H3K9me3 methylase, hairless, hairless protein, HDM, histone demethylase, histone demethylase JMJD1C, histone H3 Lys 9 demethylase, histone H3 lysine 9 demethylase, histone H3 lysine 9 Jumonji demethylase, histone H3 lysine 9 mono- and di-demethylase, histone H3K9 demethylase, histone lysine demethylase, IBM1, JHDM2A, JMJ25, JMJ27, JmjC domain-containing protein 27, jmjC histone demethylase, JmjC-domain-containing histone demethylase 2A, JMJD1A, JMJD1B, JMJD2A, Jmjd2c histone demethylase, KDM1, KDM1A, Kdm3a, Kdm3b, KDM4A, KDM7A, KIAA0601, KIAA1718, LSD1, LSD1 demethylase, LSD1/KDM1, LSD2, lysine specific demethylase 1, lysine-specific demethylase 1, lysine-specific demethylase 1A, lysine-specific demethylase 3A, lysine-specific demethylase-1, lysine-specific histone demethylase 1, lysine-specific histone demethylase 2, More, NPAO, p110b, PHF8, PHF8/KIAA1718 histone demethylase, plant homeodomain finger protein 8, SPAC23E2.02, SPBC146.09c, Suv(Var)3-9/KMT1, SWIRM1, SWIRM2, Swm1, Swm1/2 complex, Swm2, [histone-H3]-lysine-4-demethylase
ECTree
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylaseAdvanced search results
results (
results (Reference
top
Reference on EC 1.14.11.65 - [histone H3]-dimethyl-L-lysine9 demethylase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Metzger, E.; Wissmann, M.; Yin, N.; Muller, J.M.; Schneider, R.; Peters, A.H.; Gunther, T.; Buettner, R.; Schule, R.
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
Nature
437
436-439
2005
Homo sapiens
Wellmann, S.; Bettkober, M.; Zelmer, A.; Seeger, K.; Faigle, M.; Eltzschig, H.K.; Buehrer, C.
Hypoxia upregulates the histone demethylase JMJD1A via HIF-1
Biochem. Biophys. Res. Commun.
372
892-897
2008
Homo sapiens (Q9Y4C1), Rattus norvegicus (Q63679)
Okada, Y.; Scott, G.; Ray, M.K.; Mishina, Y.; Zhang, Y.
Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis
Nature
450
119-123
2007
Mus musculus (Q6PCM1)
Ishimura, A.; Terashima, M.; Kimura, H.; Akagi, K.; Suzuki, Y.; Sugano, S.; Suzuki, T.
Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene
Biochem. Biophys. Res. Commun.
389
366-371
2009
Mus musculus
Lan, F.; Shi, Y.
Epigenetic regulation: methylation of histone and non-histone proteins
Sci. China C Life Sci.
52
311-322
2009
Drosophila melanogaster, Schizosaccharomyces pombe
Perillo, B.; Ombra, M.; Bertoni, A.; Cuozzo, C.; Sacchetti, S.; Sasso, A.; Chiariotti, L.; Malorni, A.; Abbondanza, C.; Avvedimento, E.
DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
Science
319
202-206
2008
Homo sapiens
Suganuma, T.; Workman, J.
Features of the PHF8/KIAA1718 histone demethylase
Cell Res.
20
861-862
2010
Homo sapiens
Cai, Y.; Fu, X.; Deng, Y.
Histone demethylase JMJD1C regulates esophageal cancer proliferation Via YAP1 signaling
Am. J. Cancer Res.
7
115-124
2017
Homo sapiens (Q15652), Homo sapiens
El Mansouri, F.; Nebbaki, S.; Kapoor, M.; Afif, H.; Martel-Pelletier, J.; Pelletier, J.; Benderdour, M.; Fahmi, H.
Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1beta-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes
Arthritis Res. Ther.
16
R113
2014
Homo sapiens (O60341)
Shen, Y.; Pan, X.; Zhao, H.
The histone demethylase PHF8 is an oncogenic protein in human non-small cell lung cancer
Biochem. Biophys. Res. Commun.
451
119-125
2014
Homo sapiens (Q9UPP1)
Choi, J.Y.; Jo, S.A.
KDM7A histone demethylase mediates TNF-alpha-induced ICAM1 protein upregulation by modulating lysosomal activity
Biochem. Biophys. Res. Commun.
478
1355-1362
2016
Homo sapiens (Q6ZMT4), Homo sapiens
Burg, J.M.; Gonzalez, J.J.; Maksimchuk, K.R.; McCafferty, D.G.
Lysine-specific demethylase 1A (KDM1A/LSD1) product recognition and kinetic analysis of full-length histones
Biochemistry
55
1652-1662
2016
Homo sapiens (O60341)
Maina, P.K.; Shao, P.; Jia, X.; Liu, Q.; Umesalma, S.; Marin, M.; Long, D.; Concepcion-Roman, S.; Qi, H.H.
Histone demethylase PHF8 regulates hypoxia signaling through HIF1alpha and H3K4me3
Biochim. Biophys. Acta
1860
1002-1012
2017
Homo sapiens (Q9UPP1), Homo sapiens (Q9Y4C1)
Amano, Y.; Kikuchi, M.; Sato, S.; Yokoyama, S.; Umehara, T.; Umezawa, N.; Higuchi, T.
Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1
Bioorg. Med. Chem.
25
2617-2624
2017
Homo sapiens (O60341)
Pedanou, V.E.; Gobeil, S.; Tabaries, S.; Simone, T.M.; Zhu, L.J.; Siegel, P.M.; Green, M.R.
The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L
eLife
5
e16844
2016
Homo sapiens, Homo sapiens (Q9Y4C1)
Liu, L.; Kim, H.; Casta, A.; Kobayashi, Y.; Shapiro, L.; Christiano, A.
Hairless is a histone H3K9 demethylase
FASEB J.
28
1534-1542
2014
Homo sapiens, Homo sapiens (O43593)
Jiang, Y.; Wang, S.; Zhao, Y.; Lin, C.; Zhong, F.; Jin, L.; He, F.; Wang, H.
Histone H3K9 demethylase JMJD1A modulates hepatic stellate cells activation and liver fibrosis by epigenetically regulating peroxisome proliferator-activated receptor gamma
FASEB J.
29
1830-1841
2015
Homo sapiens (Q9Y4C1), Rattus norvegicus (Q63679), Rattus norvegicus Sprague-Dawley (Q63679)
Audonnet, L.; Shen, Y.; Zhou, D.
JMJ24 antagonizes histone H3K9 demethylase IBM1/JMJ25 function and interacts with RNAi pathways for gene silencing
Gene Expr. Patterns
25-26
1-7
2017
Arabidopsis thaliana, Arabidopsis thaliana (Q9SSE9), Arabidopsis thaliana Col-0 (Q9SSE9)
Liu, Z.; Chen, X.; Zhou, S.; Liao, L.; Jiang, R.; Xu, J.
The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function
Int. J. Biol. Sci.
11
494-507
2015
Mus musculus (Q6ZPY7)
Liu, Y.W.; Xia, R.; Lu, K.; Xie, M.; Yang, F.; Sun, M.; De, W.; Wang, C.; Ji, G.
LincRNAFEZF1-AS1 represses p21 expression to promote gastric cancer proliferation through LSD1-mediated H3K4me2 demethylation
Mol. Cancer
16
39
2017
Homo sapiens (O60341)
Vyas, R.N.; Meredith, D.; Lane, R.P.
Lysine-specific demethylase-1 (LSD1) depletion disrupts monogenic and monoallelic odorant receptor (OR) expression in an olfactory neuronal cell line
Mol. Cell. Neurosci.
82
1-11
2017
Mus musculus (Q6ZQ88)
Tee, A.E.; Ling, D.; Nelson, C.; Atmadibrata, B.; Dinger, M.E.; Xu, N.; Mizukami, T.; Liu, P.Y.; Liu, B.; Cheung, B.; Pasquier, E.; Haber, M.; Norris, M.D.; Suzuki, T.; Marshall, G.M.; Liu, T.
The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1
Oncotarget
5
1793-1804
2014
Homo sapiens (D6W5M4)
Qin, L.; Xu, Y.; Yu, X.; Toneff, M.; Li, D.; Liao, L.; Martinez, J.; Li, Y.; Xu, J.
The histone demethylase Kdm3a is required for normal epithelial proliferation ductal elongation and tumor growth in the mouse mammary gland
Oncotarget
8
84761-84775
2017
Mus musculus (Q6PCM1)
Dutta, A.; Choudhary, P.; Caruana, J.; Raina, R.
JMJ27, an Arabidopsis H3K9 histone demethylase, modulates defense against Pseudomonas syringae and flowering time
Plant J.
91
1015-1028
2017
Arabidopsis thaliana (Q8VYB9)
Gu, L.; Hitzel, J.; Moll, F.; Kruse, C.; Malik, R.A.; Preussner, J.; Looso, M.; Leisegang, M.S.; Steinhilber, D.; Brandes, R.P.; Fork, C.
The histone demethylase PHF8 is essential for endothelial cell migration
PLoS ONE
11
e0146645
2016
Homo sapiens (Q9UPP1)
Xiao, C.; Liu, Y.; Xie, C.; Tu, W.; Xia, Y.; Costa, M.; Zhou, X.
Cadmium induces histone H3 lysine methylation by inhibiting histone demethylase activity
Toxicol. Sci.
145
80-89
2015
Homo sapiens (Q9Y4C1)
Mimasu, S.; Sengoku, T.; Fukuzawa, S.; Umehara, T.; Yokoyama, S.
Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A
Biochem. Biophys. Res. Commun.
366
15-22
2008
Homo sapiens (O60341)
Wellmann, S.; Bettkober, M.; Zelmer, A.; Seeger, K.; Faigle, M.; Eltzschig, H.K.; Buehrer, C.
Hypoxia upregulates the histone demethylase JMJD1A via HIF-1
Biochem. Biophys. Res. Commun.
372
892-897
2008
Homo sapiens (Q9Y4C1)
Janzer, A.; Lim, S.; Fronhoffs, F.; Niazy, N.; Buettner, R.; Kirfel, J.
Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components
Biochem. Biophys. Res. Commun.
421
665-670
2012
Homo sapiens (O60341)
Gaweska, H.; Henderson Pozzi, M.; Schmidt, D.M.; McCafferty, D.G.; Fitzpatrick, P.F.
Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1
Biochemistry
48
5440-5445
2009
Homo sapiens (O60341)
Luka, Z.; Moss, F.; Loukachevitch, L.V.; Bornhop, D.J.; Wagner, C.
Histone demethylase LSD1 is a folate-binding protein
Biochemistry
50
4750-4756
2011
Homo sapiens (O60341)
Schulte, J.H.; Lim, S.; Schramm, A.; Friedrichs, N.; Koster, J.; Versteeg, R.; Ora, I.; Pajtler, K.; Klein-Hitpass, L.; Kuhfittig-Kulle, S.; Metzger, E.; Schuele, R.; Eggert, A.; Buettner, R.; Kirfel, J.
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma implications for therapy
Cancer Res.
69
2065-2071
2009
Homo sapiens (O60341)
Yamane, K.; Toumazou, C.; Tsukada, Y.; Erdjument-Bromage, H.; Tempst, P.; Wong, J.; Zhang, Y.
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
Cell
125
483-95
2006
Homo sapiens (Q9Y4C1)
Li, S.; Ali, S.; Duan, X.; Liu, S.; Du, J.; Liu, C.; Dai, H.; Zhou, M.; Zhou, L.; Yang, L.; Chu, P.; Li, L.; Bhatia, R.; Schones, D.; Wu, X.; Xu, H.; Hua, Y.; Guo, Z.; Yang, Y.; Zheng, L.; Shen, B.
JMJD1B demethylates H4R3me2s and H3K9me2 to facilitate gene expression for development of hematopoietic stem and progenitor cells
Cell Rep.
23
389-403
2018
Mus musculus
Zhu, Z.; Wang, Y.; Li, X.; Wang, Y.; Xu, L.; Wang, X.; Sun, T.; Dong, X.; Chen, L.; Mao, H.; Yu, Y.; Li, J.; Chen, P.; Chen, C.
PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis
Cell Res.
20
794-801
2010
Homo sapiens (Q9UPP1)
Qiu, J.; Shi, G.; Jia, Y.; Li, J.; Wu, M.; Li, J.; Dong, S.; Wong, J.
The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation
Cell Res.
20
908-18
2010
Homo sapiens (Q9UPP1)
Sar, A.; Ponjevic, D.; Nguyen, M.; Box, A.H.; Demetrick, D.J.
Identification and characterization of demethylase JMJD1A as a gene upregulated in the human cellular response to hypoxia
Cell Tissue Res.
337
223-234
2009
Homo sapiens (Q9Y4C1)
Lockman, K.; Taylor, J.; Mack, C.
The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression
Circ. Res.
101
e115-e123
2007
Rattus norvegicus (Q63679)
Huang, Y.; Stewart, T.M.; Wu, Y.; Baylin, S.B.; Marton, L.J.; Perkins, B.; Jones, R.J.; Woster, P.M.; Casero, R.A.
Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes
Clin. Cancer Res.
15
7217-7228
2009
Homo sapiens (O60341)
Colmenares, S.U.; Swenson, J.M.; Langley, S.3.; Kennedy, C.; Costes, S.V.; Karpen, G.H.
Drosophila histone demethylase KDM4A has enzymatic and non-enzymatic roles in controlling heterochromatin integrity
Dev. Cell
42
156-169
2017
Drosophila melanogaster (Q9V333)
Lin, H.; Zhu, X.; Chen, G.; Song, L.; Gao, L.; Khand, A.; Chen, Y.; Lin, G.; Tao, Q.
KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis
Development
144
3674-3685
2017
Xenopus laevis
Brasacchio, D.; Okabe, J.; Tikellis, C.; Balcerczyk, A.; George, P.; Baker, E.K.; Calkin, A.C.; Brownlee, M.; Cooper, M.E.; El-Osta, A.
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
Diabetes
58
1229-1236
2009
Homo sapiens (O60341), Mus musculus (Q6ZQ88), Mus musculus C57BL/6 (Q6ZQ88)
Tachibana, M.; Nozaki, M.; Takeda, N.; Shinkai, Y.
Functional dynamics of H3K9 methylation during meiotic prophase progression
EMBO J.
26
3346-3359
2007
Mus musculus (Q6PCM1)
Leisegang, M.; Gu, L.; Preussner, J.; Guenther, S.; Hitzel, J.; Ratiu, C.; Weigert, A.; Chen, W.; Schwarz, E.; Looso, M.; Fork, C.; Brandes, R.
The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G
FEBS Lett.
593
487-498
2019
Homo sapiens (Q9UPP1)
Loh, Y.; Zhang, W.; Chen, X.; George, J.; Ng, H.
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
Genes Dev.
21
2545-2557
2007
Mus musculus (Q6PCM1)
Loh, Y.H.; Zhang, W.; Chen, X.; George, J.; Ng, H.H.
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
Genes Dev.
21
254525-57
2007
Mus musculus (Q6PCM1)
Tian, Z.; Yao, L.; Shen, Y.; Guo, X.; Duan, X.
Histone H3K9 demethylase JMJD1A is a co-activator of erythropoietin expression under hypoxia
Int. J. Biochem. Cell Biol.
109
33-39
2019
Homo sapiens
Goda, S.; Isagawa, T.; Chikaoka, Y.; Kawamura, T.; Aburatani, H.
Control of histone H3 lysine 9 (H3K9) methylation state via cooperative two-step demethylation by jumonji domain containing 1A (JMJD1A) homodimer
J. Biol. Chem.
288
36948-36956
2013
Homo sapiens, Homo sapiens (Q9Y4C1)
Kim, J.; Kim, K.; Eom, G.; Choe, N.; Kee, H.; Son, H.; Oh, S.; Kim, D.; Pak, J.; Baek, H.; Kook, H.; Hahn, Y.; Kook, H.; Chakravarti, D.; Seo, S.
KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia
Mol. Cell. Biol.
32
2917-2933
2012
Homo sapiens (Q7LBC6)
Liang, Y.; Vogel, J.; Narayanan, A.; Peng, H.; Kristie, T.
Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency
Nat. Med.
15
1312-1317
2009
Homo sapiens (O60341)
Tateishi, K.; Okada, Y.; Kallin, E.; Zhang, Y.
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
Nature
458
757-761
2009
Mus musculus (Q6PCM1)
Qi, H.; Sarkissian, M.; Hu, G.; Wang, Z.; Bhattacharjee, A.; Gordon, D.; Gonzales, M.; Lan, F.; Ongusaha, P.; Huarte, M.; Yaghi, N.; Lim, H.; Garcia, B.; Brizuela, L.; Zhao, K.; Roberts, T.; Shi, Y.
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development
Nature
466
503-507
2010
Danio rerio (P0CH95), Homo sapiens (Q9UPP1)
Liu, W.; Tanasa, B.; Tyurina, O.; Zhou, T.; Gassmann, R.; Liu, W.; Ohgi, K.; Benner, C.; Garcia-Bassets, I.; Aggarwal, A.; Desai, A.; Dorrestein, P.; Glass, C.; Rosenfeld, M.
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression
Nature
466
508-512
2010
Homo sapiens (Q9UPP1)
Fan, L.; Peng, G.; Sahgal, N.; Fazli, L.; Gleave, M.; Zhang, Y.; Hussain, A.; Qi, J.
Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival
Oncogene
35
2441-2452
2015
Homo sapiens (Q9Y4C1)
Opel, M.; Lando, D.; Bonilla, C.; Trewick, S.C.; Boukaba, A.; Walfridsson, J.; Cauwood, J.; Werler, P.J.; Carr, A.M.; Kouzarides, T.; Murzina, N.V.; Allshire, R.C.; Ekwall, K.; Laue, E.D.
Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1
PLoS ONE
2
e386
2007
Schizosaccharomyces pombe (Q10135), Schizosaccharomyces pombe (Q9Y802), Schizosaccharomyces pombe, Schizosaccharomyces pombe ATCC 24843 (Q9Y802), Schizosaccharomyces pombe 972 (Q9Y802)
Zhu, Q.; Liu, C.; Ge, Z.; Fang, X.; Zhang, X.; Straat, K.; Bjoerkholm, M.; Xu, D.
Lysine-specific demethylase 1 (LSD1) is required for the transcriptional repression of the telomerase reverse transcriptase (hTERT) gene
PLoS ONE
3
e1446
2008
Homo sapiens (O60341)
Huang, Y.; Greene, E.; Murray Stewart, T.; Goodwin, A.C.; Baylin, S.B.; Woster, P.M.; Casero, R.A.
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
Proc. Natl. Acad. Sci. USA
104
8023-8028
2007
Homo sapiens (O60341)
Upadhyay, A.K.; Rotili, D.; Han, J.W.; Hu, R.; Chang, Y.; Labella, D.; Zhang, X.; Yoon, Y.S.; Mai, A.; Cheng, X.
An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases
J. Mol. Biol.
416
319-327
2012
Homo sapiens (Q6ZMT4)
Jones, D.; Wilson, L.; Thomas, H.; Gaughan, L.; Wade, M.A.
The histone demethylase enzymes KDM3A and KDM4B co-operatively regulate chromatin transactions of the estrogen receptor in breast cancer
Cancers (Basel)
11
1122
2019
Homo sapiens (Q9Y4C1)
Ding, G.; Xu, X.; Li, D.; Chen, Y.; Wang, W.; Ping, D.; Jia, S.; Cao, L.
Fisetin inhibits proliferation of pancreatic adenocarcinoma by inducing DNA damage via RFXAP/KDM4A-dependent histone H3K36 demethylation
Cell Death Dis.
11
893
2020
Homo sapiens (O75164)
Zhou, J.; Wang, F.; Xu, C.; Zhou, Z.; Zhang, W.
The histone demethylase JMJD2A regulates the expression of BDNF and mediates neuropathic pain in mice
Exp. Cell Res.
361
155-162
2017
Homo sapiens (O75164), Mus musculus (Q8BW72), Mus musculus
Zhang, Q.J.; Tran, T.A.T.; Wang, M.; Ranek, M.J.; Kokkonen-Simon, K.M.; Gao, J.; Luo, X.; Tan, W.; Kyrychenko, V.; Liao, L.; Xu, J.; Hill, J.A.; Olson, E.N.; Kass, D.A.; Martinez, E.D.; Liu, Z.P.
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
Nat. Commun.
9
5230
2018
Mus musculus (Q6PCM1)
html completed
