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1.14.11.57: L-proline trans-4-hydroxylase

This is an abbreviated version!
For detailed information about L-proline trans-4-hydroxylase, go to the full flat file.

Reaction

L-proline
+
2-oxoglutarate
+
O2
=
trans-4-hydroxy-L-proline
+
succinate
+
CO2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.57 L-proline trans-4-hydroxylase

Systematic Name

Systematic Name on EC 1.14.11.57 - L-proline trans-4-hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
L-proline,2-oxoglutarate:oxygen oxidoreductase (trans-4-hydroxylating)
Requires Fe2+ and ascorbate. The enzyme, isolated from multiple bacterial species, only produces trans-4-hydroxy-L-proline (cf. EC 1.14.11.56, L-proline cis-4-hydroxylase).