1.14.11.57: L-proline trans-4-hydroxylase This is an abbreviated version! For detailed information about L-proline trans-4-hydroxylase, go to the full flat file .
Reaction
L-proline +
2-oxoglutarate +
O2 =
trans-4-hydroxy-L-proline +
succinate +
CO2
ECTree
Systematic Name
Systematic Name on EC 1.14.11.57 - L-proline trans-4-hydroxylase
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L-proline,2-oxoglutarate:oxygen oxidoreductase (trans-4-hydroxylating)
Requires Fe2+ and ascorbate. The enzyme, isolated from multiple bacterial species, only produces trans-4-hydroxy-L-proline (cf. EC 1.14.11.56, L-proline cis-4-hydroxylase).