1.14.11.56: L-proline cis-4-hydroxylase

This is an abbreviated version!
For detailed information about L-proline cis-4-hydroxylase, go to the full flat file.

Reaction

L-proline
+
2-oxoglutarate
+
O2
=
cis-4-hydroxy-L-proline
+
succinate
+
CO2

Synonyms

cis-P4H, MlP4H, mlr6283, R03107, SmP4H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.56 L-proline cis-4-hydroxylase

Systematic Name

Systematic Name on EC 1.14.11.56 - L-proline cis-4-hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
L-proline,2-oxoglutarate:oxygen oxidoreductase (cis-4-hydroxylating)
Requires Fe2+ and ascorbate. The enzyme, isolated from Rhizobium species, only produces cis-4-hydroxy-L-proline (cf. EC 1.14.11.57, L-proline trans-4-hydroxylase).